Dissociation of Absorptions of Calcium and Phosphate in Different Pathophysiological States in Man

  • Carlo Gennari
  • Marco Bernini
  • Paolo Nardi
  • Luciana Fusi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 178)


Calcium (Ca) and inorganic phosphate (Pi) are absorbed by an active transport system, concentration and energy dependent, confined to the small intestine and depending on the presence of vitamin D.


Intestinal Absorption Postmenopausal Osteoporosis Osteoporotic Woman Tracer Method Chronic Renal Failure Patient 
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  1. 1.
    D. Schachter and S.M. Rosen, Active transport of Ca by the small intestine and its dependence on vitamin D. Amer. J. Physiol. 196: 357 (1959).PubMedGoogle Scholar
  2. 2.
    D. Schachter, E.B. Dowdle and H. Schenker, Active transport of calcium by the small intestine of the rat. Amer. J. Physiol. 198: 263 (1960).PubMedGoogle Scholar
  3. 3.
    D.V. Kimberg, D. Schachter and H. Schonker, Active transport of calcium by intestine: effects of dietary calcium. Amer. J. Physiol. 200: 1256 (1961).PubMedGoogle Scholar
  4. 4.
    D. Schachter, L’osteomalacie, in: “Vitamin D and the Intestinal Transport of Calcium and Phosphate”, D. Hioco, ed., Masson, Paris (1976).Google Scholar
  5. 5.
    R.H. Wasserman and A.N. Taylor, Some aspects of the intestinal absorption of calcium with special reference to vitamin D, in: “Mineral Metabolism - An Advanced Treatise”, C.L. Comar and F. Bronner, eds., Academic Press, New York (1969).Google Scholar
  6. 6.
    J. Harmeyer and H.F. De Luca, Calcium-binding protein and calcium absorption after vitamin D administration. Arch. Biochem. 133: 247 (1969).PubMedCrossRefGoogle Scholar
  7. 7.
    C. Gennari, Action de la vitamin D sur l’absorption digestive du calcium radio-actif chez l’homme, in: “Les Hormones et le Calcium”, H.P. Klotz, ed., Expans. Scient. Franc., Paris (1971).Google Scholar
  8. 8.
    C. Gennari, Pathologie de l’absorption intestinal du calcium at du phosphore chez l’homme, in: “Proceedings of I V Congrés Latin de Rhumatologie”, Masson, Paris (1980).Google Scholar
  9. 9.
    S.J. Birge, W.A. Peck, M. Berman and G.D. Whedon, Study of calcium absorption in man: a kinetic analysis and physiologic model. J. Clin. Invest. 48: 1705 (1969).PubMedCrossRefGoogle Scholar
  10. 10.
    R.H. Wensel, C. Rich, A.C. Brown and W. Volwiler, Absorption of calcium measured by intubation and perfusion of the intact human small intestine. J. Clin. Invest. 48: 1768 (1969).PubMedCrossRefGoogle Scholar
  11. 11.
    C.F. Cramer, Progress and rate of absorption of radiophosphorus through the intestinal tract of rats. Can. J. Biochem. Physiol. 39: 499 (1961).PubMedCrossRefGoogle Scholar
  12. 12.
    S. Kowarski and D. Schachter, Effects of vitamin D on phosphate transport and incorporation into mucosal constituents of rat intestinal mucosa. J. Biol. Chem. 244: 211 (1969).PubMedGoogle Scholar
  13. 13.
    R.H. Wasserman and A.N. Taylor, Intestinal absorption of phosphate in the chick: effect of vitamin D3 and other parameters. J. Nutr. 103: 586 (1973).PubMedGoogle Scholar
  14. 14.
    A. Caniggia and C. Gennari, L’absorption digestive du radio-phosphate chez l’homme, in: “Les Tissus Calcifiés”, G. Milhaud ed., Sedes, Paris (1968).Google Scholar
  15. 15.
    A. Caniggia and C. Gennari, Absorption du phosphate radio-actif chez l’homme et sa régulation, in: “Phosphate et Métabolisme Phosphocalcique”, D.J. Hioco, ed., Expans. Scient. Franc., Paris (1971).Google Scholar
  16. 16.
    R.H. Wasserman and R.A. Corradino, Vitamin D, calcium and protein synthesis. Vitam. Horm. 32: 43 (1973).Google Scholar
  17. 17.
    R.H. Wasserman, A.N. Taylor and C.S. Fullmer, Vitamin D-induced calcium-binding protein and the intestinal absorption of calcium, in: “The Metabolism and Function of Vitamin D”, D.R. Fraser, ed., The Biochemical Society, London (1974).Google Scholar
  18. 18.
    R. Wilkinson, Absorption of calcium, phosphorus and magnesium, in: “Calcium Phosphate and Magnesium Metabolism”, B.E.C. Nordin ed., Churchill Livingstone, Edinburg (1976).Google Scholar
  19. 19.
    E.M. Short, H.J. Binder and L.E. Rosenberg, Familial hypophosphataemic rickets: defective transport of inorganic phosphates by intestinal mucosa. Science 179: 700 (1973).PubMedCrossRefGoogle Scholar
  20. 20.
    R. Wootton and J. Reeve, The relative merits of various techniques for measuring radiocalcium absorption. Clin. Sci. 58: 287 (1980).PubMedGoogle Scholar
  21. 21.
    D.H. Marshall and B.E.C. Nordin, A comparison of radioactive calcium absorption tests with net calcium absorption. Clin. Sci. 61: 477 (1981).PubMedGoogle Scholar
  22. 22.
    K. Farrington, M.N. Mohammed, S.P. Newman, Z. Varghese and J.F. Moorhead, Comparison of radioisotope methods for the measurement of phosphate absorption in normal subjects and in patients with chronic renal failure. Clin. Sci. 60: 55 (1981).PubMedGoogle Scholar
  23. 23.
    M. Peacock, A.M. Davison and G.S. Walker, The effects of plasma phosphate on the action of 1αOHD3 in haemodialysis patients. Adv. Exp. Med. Biol. 81: 559 (1977).Google Scholar
  24. 24.
    D.H. Marshall and B.E.C. Nordin, Kinetic analysis of plasma radioactivity after oral ingestion of radiocalcium. Nature 222: 797 (1969).PubMedCrossRefGoogle Scholar
  25. 25.
    K. Farrington, Z. Varghese, S.P. Newman, K.Y. Ahmed, O.N. Fernando and J.F. Moorhead, Dissociation of absorptions of calcium and phosphate after successful cadaveric renal transplantation. Brit. Med. J. 1: 712 (1979).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Carlo Gennari
    • 1
  • Marco Bernini
    • 1
  • Paolo Nardi
    • 1
  • Luciana Fusi
    • 1
  1. 1.Institute of Medical SemeioticsUniversity of SienaItaly

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