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Different Effects of Parathyroid Hormone on Epithelial Transport

  • Sandra Sabatini
  • Roger Mola
  • James T. McCreary
  • Neil A. Kurtzman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 178)

Abstract

Parathyroid hormone (PTH) has been shown to stimulate calcium (Ca) transport in many tissues including human red cells, cultured heart cells, isolated mitochondria, Hela cells, renal and Ehrlich ascites tumor cells (1–7). The effect of PTH on calcium transport appears to be independent of activation adenylate cyclase (8). Because of these findings, we proposed that PTH may act as a naturally occurring calcium ionophore (8).

Keywords

Parathyroid Hormone Calcium Ionophore Calcium Transport Sodium Transport Parathyroid Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bogin E, Massry SG, Levi J, Djaldeti M, Bristol G, Smith J: Effect of parathyroid hormone on osmotic fragility of human erythrocytes. J Clin Invest 69: 1017, 1982.PubMedCrossRefGoogle Scholar
  2. 2.
    Meytes D, Bogin E, Ma A, Dukes PP, and Massry SG: Effect of parathyroid hormone on erythropoiesis. J. Clin. Invest. 67: 1263, 1981.PubMedCrossRefGoogle Scholar
  3. 3.
    Chausmer AB, Sherman BS, Wallach S: The effect of parathyroid hormone on hepatic cell transport of calcium. Endocrinology 90: 663, 1972.PubMedCrossRefGoogle Scholar
  4. 4.
    Tenebause A, Meier H, Rasmussen H: Parathyroid hormone and bone mobilization in vitro. J Biol Chem 241: 1314, 1966.Google Scholar
  5. 5.
    Borle AB: Calcium metabolism in Hela cells and the effect of parathyroid hormone. J Cell Biol 36: 567, 1968.PubMedCrossRefGoogle Scholar
  6. 6.
    Borle AB: Calcium metabolism at the cellular level. Fed Proc 32: 1955, 1973.Google Scholar
  7. 7.
    Borle AB: Parathyroid hormone and cell calcium. In Calcium, Parathyroid Hormone, and the Calcitonins, eds Talmage RV and Munson RL. Amsterdam, Excerpta Medical Foundation, 484, 1972.Google Scholar
  8. 8.
    Sabatini S, McCreary JT, Kurtzman NA: Parathyroid hormone - a naturally occurring Ca ionophore. Clin Res 30: 788A, 1982.Google Scholar
  9. 9.
    Arruda JAL, Sabatini S: Effect of quinidine on Na, H+ and water transport by the turtle and toad bladders. J Membrane Biol 55: 141, 1980.CrossRefGoogle Scholar
  10. 10.
    Arruda JAL, Sabatini S: Cholinergic modulation of water transport in the toad bladder. Amer J Physiol 239: F154, 1980.PubMedGoogle Scholar
  11. 11.
    Arruda JAL, Sabatini S: Cholinergic inhibition of urinary acidification by the turtle bladder. Kidney Internat 17: 622, 1980.CrossRefGoogle Scholar
  12. 12.
    Sabatini S, Arruda JAL: Calcium and membrane transport. In The Role of Calcium in Biological Systems, eds Anghileri LJ and Truffet-Anghileri AM, vol 2. Boca Raton, CRC Press Inc, 2, 1982.Google Scholar
  13. 13.
    Clark NB: Experimental and histologic studies of the parathyroid glands of fresh-water turtles. Gen Compar Endocrinol 5: 297, 1965.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Sandra Sabatini
    • 1
  • Roger Mola
    • 1
  • James T. McCreary
    • 1
  • Neil A. Kurtzman
    • 1
  1. 1.Departments of Medicine & PhysiologyUniversity of Illinois College of MedicineChicagoUSA

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