The Assessment of Renal Calcium Reabsorption

  • O. L. M. Bijvoet
  • H. I. J. Harinck
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 178)


Renal clearances studies rest upon comparisons of concentrations in the plasma (P; mass/vol) with simultaneously measured urinary excretion rates (UV; mass/time). Their value depends on adequacy of the assumption, that the function that relates excretion rate to plasma concentration, contains a minimum of variables and, that those variables are relevant as to the behaviour of the Kidney.


Glomerular Filtration Rate Fractional Excretion Primary Hyperparathyroidism Renal Handling Calcium Reabsorption 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Smith, P.K., Ollayos, R.W., Winkler, A.W. Tubular reabsorption of phosphate in the dog. J.Clin.Invest. 22: 143 (1943).PubMedCrossRefGoogle Scholar
  2. 2.
    Pitts, R.F. A renal reabsorptive mechanism in the dog common to glycine and creatinine. Amer.J.Physiol. 140: 156 (1943).Google Scholar
  3. 3.
    Massry, S.G., Coburn, J.W., Kleeman, C.R. Renal handling of magnesium in the dog. Amer.J.Physiol. 216: 1460 (1969).PubMedGoogle Scholar
  4. 4.
    Bijvoet, O.L.M. Relation of plasma phosphate concentration to renal tubular reabsorption of phosphate. Clin.Sci. 37: 23 (1969).PubMedGoogle Scholar
  5. 5.
    Bijvoet, O.L.M. Measurement of renal handling of phosphate. In: Renal handling of Phosphate, edited by S.G. Massry and H.Fleisch; Plenum Medical Book Cy. New York, 1980, pp. 1–37.CrossRefGoogle Scholar
  6. 6.
    Bijvoet, O.L.M., Morgan, D.B. The tubular reabsorption of phosphate in man. In: Phosphate et Métabolisme Phosphocalcique, edited by D.J. Hiocco; L’Expansion Scientifique Francaise, Paris, 1971, pp. 153–80.Google Scholar
  7. 7.
    Walton, R.J., Bijvoet, O.L.M. Nomogram for the derivation of renal threshold phosphate concentration. Lancet 2: 309 (1975).PubMedCrossRefGoogle Scholar
  8. 8.
    Mioni, G., d’Angelo, A., Ossi, E., Bertaglia, E., Marconi, G., Maschio, G. The renal handling of calcium in normal Subjects and in renal disease. Rev.Eur.Etud.Clin.Biol. 16: 881 (1971).PubMedGoogle Scholar
  9. 9.
    Marshall, R.W. Calcium fraction in Plasma. In: Calcium, Phosphate and Magnesium Metabolism. Edited by B.E.C. Nordin, Churchill, London, 1976, pp. 162–178.Google Scholar
  10. 10.
    Bijvoet, O.L.M. Kidney function in Calcium and Phosphate Metabolism. In: Metabolic Bone Disease I, Edited by L.V. Avioli and S.M. Krane. Academic Press Inc., New York, 1977, pp. 49–140.Google Scholar
  11. 11.
    Marshall, D.H. Calcium and Phosphate Kinetics. In: Calcium, Phosphate and Magnesium Metabolism. Edited by B.E.C. Nordin, Churchill, London, 1976, pp. 257–297.Google Scholar
  12. 12.
    Le Grimmellec, C., Roinel, N., Morel, F. Simultaneous Mg, Ca, P, K, Na and Cl analysis in rat tubular fluid. III, During acute Ca plasma loading. Pflügers Arch. 346: 171 (1974).CrossRefGoogle Scholar
  13. 13.
    Edwards, B.R., Sutton, R.A.L., Dirks, J.H. Effect of calcium infusion on renal tubular reabsorption in the dog. Amer. J. Physiol. 227: 13 (1974).PubMedGoogle Scholar
  14. 14.
    Frijlink, W.B., Bijvoet, O.L.M., Te Velde, J., Heynen, G. Treatment of Paget’s disease with (3-amino-l-hydroxypropylidene)I,1-bisphosphonate (APD). Lancet i:799(1979).CrossRefGoogle Scholar
  15. 15.
    Adami, S., Frijlink, W.B., Bijvoet, O.L.M., O’Riordan, J.L.H., Clemens, T.L., Papapoulos, S.E. Regulation of Calcium Absorption by 1,25 Dihydroxy-Vitamin D-Studies of the Effects of a Bisphosphonate Treatment. Calcif.Tiss. Int. 34: 317 (1982).CrossRefGoogle Scholar
  16. 16.
    Marshall, D.H., Peacock, M., Nordin, B.E.C. Plasma calcium homeostasis. In: Rein et Calcium, edited by D. Hioco, Rueil-Malmaison: Sandoz Editions (1973) pp. 15–25.Google Scholar
  17. 17.
    Peacock, M., Robertson, W.G., Nordin, B.E.C. Relation between serum and urinary calcium with particular reference to parathyroid hormone. Lancet 1: 384 (1969).PubMedCrossRefGoogle Scholar
  18. 18.
    Fanelli, G.M., Jr., Hohn, D.L., Stafford, S. Functional characteristics of renal urate transport in the Cebus Monkey. Amer.J.Physiol. 218: 627 (1970).PubMedGoogle Scholar
  19. 19.
    Shannon, J.A. The excretion of phenol red by the dog. Amer.J.Physiol. 113: 602 (1935).Google Scholar
  20. 20.
    Shannon, J.A. On the mechanism of the renal tubular excretion of creatinine in the dog fish, squalus acanthias. J.Cell. and Comp.Physiol. 16: 285 (1940).CrossRefGoogle Scholar
  21. 21.
    Bijvoet, O.L.M., Harinck, H.I.J. in preparation.Google Scholar
  22. 22.
    Menko, F.H., Bijvoet, O.L.M., Fronen, J.L.H.H., Sandler, L.M., Adami, S., O’Riordan, J.L.H., Schopman, P. and Heynen, G. Familial benign hypercalcemia. Study of a large family. Quarterly J. of Medicine, in press. (1983)Google Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • O. L. M. Bijvoet
    • 1
  • H. I. J. Harinck
    • 1
  1. 1.Clinical Investigation Unit of the Dept. of EndocrinologyUniversity HospitalLeidenThe Netherlands

Personalised recommendations