The Usefulness of Isolated Renal Cortical Cells to Study Phosphate Transport

  • Nicole Tessitore
  • Lakhi M. Sakhrani
  • Shaul G. Massry
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 178)


Much of the work on the metabolic support of transport in the kidney has utilized renal homogenates, renal slices and isolated renal tubules. However, these are not ideal systems because of their limited luminal access for transport and/or their anaerobic nature. Isolated perfused kidney and microperfused tubular segments have also been used for this purpose and do not have the above disadvantages. A useful additional tool is the use of isolated renal cells in suspension, in which access to luminal transporters and diffusion of oxygen would not be limiting.


Cortical Tubule Cytosolic Redox Renal Homogenate Renal Gluconeogenesis Zealand White Male Rabbit 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Nicole Tessitore
    • 1
  • Lakhi M. Sakhrani
    • 1
  • Shaul G. Massry
    • 1
  1. 1.Division of NephrologyUniversity of Southern California, School of MedicineLos AngelesUSA

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