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Use of Autoradiographic Techniques for the Localization of Neurotransmitter Receptors in Brain and Periphery: Recent Applications

  • D. R. Gehlert
  • H. I. Yamamura
  • J. K. Wamsley
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 160)

Abstract

The role of the receptor in mediating drug and neurotransmitter action has become increasingly more well-defined. Studies of a compound’s interaction with its receptor has led to the concept of rational drug design and subsequent in vitro testing procedures. Anatomical localization of these drug and neurotransmitter receptors can lead to an increased understanding of their potential role in physiological and behavioral responses, as well as helping to define mechanisms of drug action.

Keywords

Amyotrophic Lateral Sclerosis Muscarinic Receptor Axonal Transport Neurotransmitter Receptor Muscarinic Antagonist 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • D. R. Gehlert
    • 1
    • 2
  • H. I. Yamamura
    • 1
    • 2
  • J. K. Wamsley
    • 1
    • 2
  1. 1.Departments of Psychiatry, Anatomy and PharmacologyUniversity of Utah School of MedicineSalt Lake CityUSA
  2. 2.Departments of Pharmacology, Biochemistry, Psychiatry and the Arizona Research LaboratoriesUniversity of Arizona Health Science CenterTucsonUSA

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