Nerve Growth-Promoting Activities in Embryonic and Adult Tissues
Methods to establish the presence in tissues of nerve growth factor (NGF) and other promoters of nerve fiber growth are described. Evidence for a NGF-like activity in the rat iris and sciatic nerve obtained by bioassay is reviewed. Data are presented to indicate that the iris of the adult chick can also produce a NGF-like factor in culture. It is described that many tissues from the rat and embryonic chick contain additional substances eliciting fiber outgrowth in ciliary neurons not susceptible to the actions of NGF.
KeywordsNerve Growth Factor Sciatic Nerve Chick Embryo Sympathetic Ganglion Fiber Outgrowth
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