Cellular Interactions and the Survival and Maintenance of Neurons During Development

  • Ronald W. Oppenheim
Part of the NATO ASI Series book series (NSSA, volume 78)


Perhaps the most fundamental organizing principle of the developing nervous system is the role of cell and tissue interactions in regulating the countless steps leading from the zygote to the adult. Virtually nothing in the entire field of neuroembryology makes much sense if viewed from a perspective that is devoid of an appreciation of the pervasiveness of cell-to-cell inter-relationships. Starting with the origins of the nervous system during primary induction and continuing up to the final stages of neurobehavioral development no stage or event in neurogenesis is ever entirely independent of the influence of cellular interactions.


Nerve Growth Factor Neuronal Death Chick Embryo Neuromuscular Blockade Spinal Motoneuron 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Ronald W. Oppenheim
    • 1
    • 2
  1. 1.Department of Anatomy Bowman Gray School of MedicineWake Forest UniversityWinston SalemUSA
  2. 2.Neurobiology ProgramUniversity of North CarolinaChapel HillUSA

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