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Ordered Nerve Connections: Pathways and Maps

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Organizing Principles of Neural Development

Part of the book series: NATO ASI Series ((NSSA,volume 78))

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Abstract

The idea that orderly neuronal interconnections are based on chemoselective recognition between the cells and their processes was proposed by Cajal (1892) and given experimental support by the work of Langley (1895). In its present form the hypothesis of neuronal specificity, as it is now called, derives largely from the work of Sperry (1943; 1944; 1945; 1951; 1963; 1965) and it proposes that interconnecting populations of neurones each acquire positionally dependent chemoselectivity labels, or markers, early in development, and that properly ordered interconnections between the populations are based on selective affinities between the markers carried by one population and those carried by the other.

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Authors and Affiliations

  1. National Institute for Medical Research, The Ridgeway, Mill Hill, London, England

    R. M. Gaze

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  1. R. M. Gaze
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Editors and Affiliations

  1. New York Medical College, Valhalla, New York, USA

    S. C. Sharma

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© 1984 Plenum Press, New York

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Gaze, R.M. (1984). Ordered Nerve Connections: Pathways and Maps. In: Sharma, S.C. (eds) Organizing Principles of Neural Development. NATO ASI Series, vol 78. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4802-3_19

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  • DOI: https://doi.org/10.1007/978-1-4684-4802-3_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4804-7

  • Online ISBN: 978-1-4684-4802-3

  • eBook Packages: Springer Book Archive

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