Biomembranes pp 179-192 | Cite as

Membrane-Bound Phospholipases: Properties and Functions

  • Peter Zahler
  • Donald Käsermann
  • Markus Reist
Part of the NATO ASI Series book series (NSSA, volume 76)


Already 100 years ago the existence of a lipid-splitting enzyme from pancreatic juice was postulated. In 1903 it was known that cobra venom converted lecithin into a strongly haemolytic product. Systematic studies on the phospholipid-splitting enzymes (phospholipases, P’Lases) started, however, only some 30 years ago, initially on soluble enzymes (pancreatic P’Lase A and venoms). Only later were cellular-soluble and membrane-bound P’Lases discovered and characterized.


Arachidonic Acid Pancreatic Juice Human Platelet Rabbit Platelet Cobra Venom 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Peter Zahler
    • 1
  • Donald Käsermann
    • 1
  • Markus Reist
    • 1
  1. 1.Institute of BiochemistryUniversity of BerneBerneSwitzerland

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