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Nutritional and Toxicological Aspects of Food Safety pp 91–113Cite as

Role of Epigenetic Factors in Dietary Carcinogenesis

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 177))

Abstract

Sixty to eighty percent of all human cancers are associated with our environment and environmental agents. The environment is a complex mixture of chemicals that originate from industrial and technological development and, most importantly, natural sources. Many industrial chemicals, pesticides, insecticides and food additives have exhibited carcinogenic properties in various animal model systems, and occupational and drug exposure has led to human cancers. However, estimates attribute the majority of human cancers associated with the environment not to intentional or accidental chemical exposure, but to the vast number of naturally occurring chemicals in our environment (Doll and Peto, 1981).

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Authors and Affiliations

  1. WRRC, Toxicology & Biological Evaluation Research Unit, United States Department of Agriculture, 800 Buchanan Street, Berkeley, CA, 94710, USA

    David L. Berry

  2. Biological and Environmental Chemistry Department Life Sciences Division, SRI International, 333 Ravenswood Avenue, Menlo Park, CA, 94025, USA

    C. Tucker Helmes

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  1. David L. Berry
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  1. Agricultural Research Service Western Regional Research Center, U.S. Department of Agriculture, Berkeley, California, USA

    Mendel Friedman

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Berry, D.L., Helmes, C.T. (1984). Role of Epigenetic Factors in Dietary Carcinogenesis. In: Friedman, M. (eds) Nutritional and Toxicological Aspects of Food Safety. Advances in Experimental Medicine and Biology, vol 177. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4790-3_4

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