A Possible Role for Excitatory Neurotoxic Amino Acids in the Pathogenesis of Hepatic Encephalopathy

  • F. Moroni
  • G. Lombardi
  • G. Moneti
  • D. Pellegrini
  • C. Cortesini


Extensive research in the past few years has been directed towards understanding the role of acidic excitatory amino acids in the pathogenesis of several neurological and psychiatric disorders.1–3 However, relatively little information is available on the role of glutamic acid (GLU), the prototype of acidic excitatory amino acids, in the pathogenesis of hepatic encephalopathy.4


Glutamic Acid Hepatic Encephalopathy Caudate Nucleus Hepatic Coma Chronic Liver Failure 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • F. Moroni
    • 3
  • G. Lombardi
    • 1
  • G. Moneti
    • 3
  • D. Pellegrini
    • 1
  • C. Cortesini
    • 2
  1. 1.Departments of PharmacologyFirenzeItaly
  2. 2.Departments of SurgeryFirenzeItaly
  3. 3.The Mass-Spectrometry Centre of the Medical SchoolFirenzeItaly

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