Abstract
The mechanism of hepatic encephalopathy (HE) is still unknown. A characteristic amino acid pattern in HE has been described: an increased level of plasma free tryptophan, a fall in plasma branched chain amino acids (BCAA) valine, leucine and isoleucine and a rise in plasma aromatic amino acids (AAA) phenylalanine and tyrosine.1 The brain uptake of AAA would increase; the ensuing depletion of brain dopamine and norepinephrine and increase of brain octopamine, which is considered as a false neurotransmitter, would result in perturbation of cerebral neurotransmission.2
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© 1984 Plenum Press, New York
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Michel, H., Pomier-Layrargues, G., Aubin, J.P., Bories, P., Mirouze, D., Bellet-Hermann, H. (1984). Treatment of Hepatic Encephalopathy by Infusion of a Modified Amino Acid Solution: Results of a Controlled Study in 47 Cirrhotic Patients. In: Capocaccia, L., Fischer, J.E., Rossi-Fanelli, F. (eds) Hepatic Encephalopathy in Chronic Liver Failure. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4787-3_31
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DOI: https://doi.org/10.1007/978-1-4684-4787-3_31
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