Proteins and Amino Acids in Liver Failure

  • G. Marchesini
  • M. Zoli
  • C. Dondi
  • G. P. Bianchi


Patients with liver cirrhosis scarcely tolerate protein thus large nitrogen loads are likely to induce hepatic coma. A protein load, either as a protein rich meal or a gastrointestinal bleeding, which increase nitrogen reabsorption, or an intravenous administration of protein hydrolisates, may produce stupor and drowsiness up to deep coma, at the same time increasing blood ammonia. This clinical observation forms the basis of the ‘ammonia’ theory of hepatic encephalopathy.


Liver Cirrhosis Hepatic Encephalopathy Aromatic Amino Acid Plasma Amino Acid Hepatic Coma 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • G. Marchesini
    • 1
  • M. Zoli
    • 1
  • C. Dondi
    • 1
  • G. P. Bianchi
    • 1
  1. 1.Istituto di Patologia Medica 1Università di Bologna Policlinico S. OrsolaBolognaItaly

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