Cross-Gender Identity in a Broader Context

  • Kurt Freund
Part of the Perspectives in Sexuality book series (PISE)

Abstract

This chapter is a review of clinical and experimental studies that may suggest questions useful in research on the etiology of cross-gender identity (which is here conceived as an extreme form of masculine gender identity in females or feminine gender identity in males). The first section addresses itself to the typology of cross-gender identity and demonstrates that there are two main types, one occurring in homosexual, the other in heterosexual (or just nonhomosexual) persons. Next, the relationships among androphilia (an erotic preference for physically mature males), homosexual-type cross-gender identity, and feminine gender identity (in males) in general are explored. The second section investigates the feasibility of physiological hypotheses of homosexual cross-gender identity and discusses, in this context, relevant work on the development of gender identity in intersexes. The third section explores the relevance of animal studies to the problem of gender identity.

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References

  1. Ägmo, A. The comparative actions of fluoxymesterone and testosterone on sexual behavior and accessory sexual glands in castrated rabbits. Horm Behav, 9:112–119, 1977.PubMedCrossRefGoogle Scholar
  2. Alsum, P., & Coy, R. W. Actions of esters of testosterone, dihydrotestosterone, or estradiol on sexual behavior in castrated male guinea pigs. Horm Behav, 5:207–217, 1974.PubMedCrossRefGoogle Scholar
  3. Ancel, P., & Bouin, P. Histogenese de la glande interstitielle du testicule chez le pore. C R Soc Biol, 55:1680–1682, 1903.Google Scholar
  4. Anchersen, P. Problems of transvestism. Acta Psychiatr Neurol Scand (Suppl), 106:249–256, 1956.Google Scholar
  5. Arai, Y., & Gorski, R. A. Protection against the neural organizing effect of exogenous androgen in the neonatal female rat. Endocrinology, 82:1005–1009, 1968.PubMedCrossRefGoogle Scholar
  6. Arnold, A. P. Sexual differences in the brain. Am Sci, 68:165–173, 1980.PubMedGoogle Scholar
  7. Ball, J. The effect of male hormone on the sex behavior of female rats. Psychol Bull, 34:725, 1937. (a)Google Scholar
  8. Ball, J. Sex activity of castrated male rats increased by estrin administration. J Comp Psychol, 24:135–144, 1937. (b)CrossRefGoogle Scholar
  9. Ball, J. R. B. Thirty years experience with transsexualism. Aust NZ J Med, 15:39–43, 1981.Google Scholar
  10. Bates, J. E., & Bentler, P. M. Play activities of normal and effeminate boys. Dev Psychol, 9:20–27, 1973.CrossRefGoogle Scholar
  11. Bateson, G. Naven. Cambridge, England: The University Press, 1936.Google Scholar
  12. Baum, M. J., & Vreeburg, J. T. M. Copulation in castrated male rats following combined treatment with estradiol and dihydrotesterone. Science, 182:283–285, 1973.PubMedCrossRefGoogle Scholar
  13. Beach, F. A. Sex reversals in the mating pattern of the rat. J Gen Psychol, 53:329–334, 1938.Google Scholar
  14. Beach, F. A. Female mating behavior shown by male rats after administration of testosterone propionate. Endocrinology, 29:409–412, 1941.CrossRefGoogle Scholar
  15. Beach, F. A. Bisexual mating behavior in the male rat: Effects of castration and hormone administration. Physiol Zool, 18:390–402, 1945.Google Scholar
  16. Beach, F. A. Hormones and Behavior. New York: Paul Hoeber, 1948.Google Scholar
  17. Beach, F. A. Hormonal modification of sexually dimorphic behavior. Psychoneuroendocrinology, 1:3–23, 1975.CrossRefGoogle Scholar
  18. Beach, F. A. Hormonal control of sex-related behavior. In F. Beach (Ed.):Human Sexuality in Four Perspectives. Baltimore: Johns Hopkins University Press, 1976.Google Scholar
  19. Beach, F. A. Hormones and Behavior. New York: Paul Hoeber, 1948.Google Scholar
  20. Beach, F. A. Male and female mating behavior in prepubertally castrated female rats treated with androgen. Endocrinology, 31:673–678, 1942.CrossRefGoogle Scholar
  21. Beach, F. A., & Holz, A. M. Mating behavior in male rats castrated at various ages and injected with androgen. J Exp Zool, 101:91–142, 1946.PubMedCrossRefGoogle Scholar
  22. Beach, F. A., & Rasquin, P. Masculine copulatory behavior in intact and castrated female rats. Endocrinology, 31:393–409, 1942.CrossRefGoogle Scholar
  23. Beach, F. A., & Westbrook, W. H. Morphological and behavioural effects of an antiandrogen’ in male rats. J Endocrinol, 42:379–382, 1968.PubMedCrossRefGoogle Scholar
  24. Beach, F. A., Noble, R. G., & Orndorff, R. K. Effects of perinatal androgen treatment on responses of male rats to gonadal hormones in adulthood. J Comp Physiol Psychol, 68:490–497, 1969.PubMedCrossRefGoogle Scholar
  25. Beach, F. A., & Kuehn, R. E. Coital behavior in dogs. X. Effects of androgenic stimulation during development on feminine mating responses in females and males. Horm Behav, 1:347–368, 1970.CrossRefGoogle Scholar
  26. Beach, F. A., Kuehn, R. E., Sprague, R. H., & Anisko, J. J. Coital behavior in dogs. XI. Effects of androgenic stimulation during development on masculine mating responses in females. Horm Behav, 3:143–168, 1972.PubMedCrossRefGoogle Scholar
  27. Beach, F. A., Johnson, A. I., Anisko, J. J., & Dunbar, I. F. Hormonal control of sexual attraction in pseudohermaphroditic female dogs. J Comp Physiol Psychol, 91:711–715, 1977.PubMedCrossRefGoogle Scholar
  28. Bechterev, V. M. Die Funktionen der Nervencentra (Band 2). Jena: Fischer, 1909.Google Scholar
  29. Benjamin, H. The Transsexual Phenomenon. New York: Julian Press, 1966.Google Scholar
  30. Benjamin, H. Should surgery be performed on transsexuals? Am J Psychother, 25:74–82, 1971.PubMedGoogle Scholar
  31. Bereu, B. B., Donahoe, P. K., & Shulman, J. D. New insights into abnormal sexual differentiation. Contemp Ob/Gyn, 16:159–162, 1980.Google Scholar
  32. Berthold, A. A. Transplantation der Hoden. Archiv für Anatomie Physiologie und Wissenchaftliche Medizin, 16:42–46, 1849.Google Scholar
  33. Beyer, C., Morali, G., Naftolin, F., Larsson, K., & Perez-Palacios, G. Effects of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats. Horm Behav, 7:353–363, 1976.PubMedCrossRefGoogle Scholar
  34. Beyer, C., & Rivaud, N. Differential effect of testosterone and dihydrotestosterone on the sexual behavior of prepuberally castrated male rabbits. Horm Behav, 4:175–180. 1973.CrossRefGoogle Scholar
  35. Bhaskaran, K. Psychosexual identification in the epilepsies. J Nerv Ment Dis, 121:230–235, 1955.PubMedCrossRefGoogle Scholar
  36. Birns, B. The emergence and socialization of sex differences in the earliest years. Merrill-Palmer Q, 22:229–254, 1976.Google Scholar
  37. Blizard, D., & Denef, C. Neonatal androgen effects on open-field activity and sexual behavior in the female rat: The modifying influence of ovarian secretions during development. Physiol Behav, 11:65–69, 1973.PubMedCrossRefGoogle Scholar
  38. Bouin, P., and Ancel, P. Sur la signification de la glande interstitielle du testicule embryonnaire. C R Soc Biol, 55:1682–1684, 1903.Google Scholar
  39. Bräutigam, W. Körperliche, seelische und soziale Einflüsse auf die Geschlechtszugehörigkeit des Menschen. Der Internist, 5:171–182, 1964.Google Scholar
  40. Brown, D. G. Sex-role preference in young children. Psychol Monogr, 70:1–19, 1956.CrossRefGoogle Scholar
  41. Brown, T. R., Maes, M., Rothwell, S. W., & Migeon, G. J. Human complete androgen insen- sitivity with normal dihydrotestosterone receptor binding capacity in cultured genital skin fibroblasts: Evidence for a qualitative abnormality of the receptor. J Clin Endocrinol Metab, 55:61–69, 1982.PubMedCrossRefGoogle Scholar
  42. Bubenik, G. A., & Brown, G. M. Morphologic sex differences in primate brain areas involved in regulation of reproductive activity. Experientia, 29:619–621, 1973.PubMedCrossRefGoogle Scholar
  43. Buhrich, N. A case of familial heterosexual transvestism. Acta Psychiatr Scand, 55:199–201, 1977.PubMedCrossRefGoogle Scholar
  44. Buhrich, N., & McGonaghy, N. Can fetishism occur in transsexuals? Arch Sex Behav, 6:223–235, 1977. (a)PubMedCrossRefGoogle Scholar
  45. Buhrich, N., & McGonaghy, N. The discrete syndromes of transvestism and transsexualism. Arch Sex Behav, 6:483–496, 1977. (b)PubMedCrossRefGoogle Scholar
  46. Buhrich, N., & McGonaghy, N. Two clinically discrete syndromes of transsexualism. Br J Psychiatry, 133:73–76, 1978.PubMedCrossRefGoogle Scholar
  47. Buhrich, N., & McGonaghy, N. Three clinically discrete categories of fetishistic transvestism. Arch Sex Behav, 8:151–157, 1979.PubMedCrossRefGoogle Scholar
  48. Butcher, L. L., Butcher, S. G., & Larsson, K. Effects of apomorphine (+)-amphetamine, and nialamide on tetrabenazine-induced suppression of sexual behavior in the male rat. Eur f Pharmacol, 7: 283–288, 1969.CrossRefGoogle Scholar
  49. Carter, C. S., & Davis, J. M. Biogenic amines, reproductive hormones and female sexual behavior: A review. Biobehav Rev, 1: 213–224, 1977.CrossRefGoogle Scholar
  50. Christensen, L. W., & Clemens, L. C. Blockade of testosterone-induced mounting behavior in the male rat with intracranial application of the aromatization inhibitor, androst-l,4,6-triene-3, 17- dione. Endocrinology, 97:1545–1551, 1975.PubMedCrossRefGoogle Scholar
  51. Christensen, L. W., Nance, D. M., & Gorski, R. A. Effects of hypothalamic and preoptic lesions on reproductive behavior in male rats. Brain Res Bull, 2:137–141, 1977.PubMedCrossRefGoogle Scholar
  52. Christensen, L. W., & Gorski, R. A. Independent masculinization of neuroendocrine or estradiol in the neonatal female rat. Brain Res, 146:325–340, 1978.PubMedCrossRefGoogle Scholar
  53. Clark, L. P. The nature and pathogenesis of epilepsy. NY State J Med, 101:385–392, 442–448, 515–522, 567–573, 623–628, 1915.Google Scholar
  54. Clemens, L. G., & Gladue, B. A. Feminine sexual behavior in rats enhanced by prenatal inhibition of androgen aromatization. Horm Behav, 11:190–201, 1978.PubMedCrossRefGoogle Scholar
  55. Clemens, L. G., Hiroi, M., & Gorski, R. A. Induction and facilitation of female mating behavior in rats treated neonatally with low doses of testosterone propionate.Endocrinology, 84:1430–1438, 1969.PubMedCrossRefGoogle Scholar
  56. Dantchakoff, V. Role des hormones dans la manifestation des instincts sexuels. C R Acad Sci, 206:945–947, 1938. (a)Google Scholar
  57. Dantchakoff, V. Sur les effects de Thormone male dans une jeune cobaye femelle traitee depuis un Stade embryonnaire (Inversions sexuelles). C R Soc Biol, 127:1255–1259, 1938. (b)Google Scholar
  58. Dantchakoff, V. Sur les mecanismes differentiels dans la realisation des sexes chez les vertebres superieurs (singe, Macacus rhesus). Bull Biol Fr Belg, 84:311–340, 1950.Google Scholar
  59. Davenport, W. Sexual patterns and their regulation in a society of the Southwest Pacific. In F. A. Beach (Ed.): Sex and Behavior. New York: John Wiley, 1965.Google Scholar
  60. Davidson, J. M. Activation of male rat’s sexual behavior by intracerebral implantation of androgen. Endocrinology, 79:783–794, 1966.PubMedCrossRefGoogle Scholar
  61. Davidson, J. M., & Levine, S. Progesterone and heterotypical sexual behaviour in male rats. J Endrocrinol, 44:129–130, 1969.CrossRefGoogle Scholar
  62. Davidson, J. M., & Trupin, S. Neural medication of steroid-induced sexual behavior in rats. In M. Sandler & G. L. Gessa (Eds.): Sexual Behavior: Pharmacology and Biochemistry. New York: Raven Press, 1975.Google Scholar
  63. Davies, M. B., & Morgenstern, F. S. A case of cysticercosis, temporal lobe epilepsy and transvestism. J Neurol Neurosurg Psychiatry, 23:247–249, 1960.PubMedCrossRefGoogle Scholar
  64. DeBold, J. F., & Clemens, L. G. Aromatization and the induction of male sexual behavior in male, female, and androgenized female hamsters. Horm Behav, 11:401–413, 1978.PubMedCrossRefGoogle Scholar
  65. De Jongh, S. E., & Mulder, J. D. Uber die Maskulinisierung der äusseren Genitalien von weiblichen Meerschweinchen nach Injektion von männlichem Hormon. Endokrinologie, 2:161–165, 1932.Google Scholar
  66. Diamond, M., & Young, W. C. Differential responsiveness of pregnant and nonpregnant guinea pigs to the masculinizing action of testosterone propionate. Endocrinology, 72:429, 1963.PubMedCrossRefGoogle Scholar
  67. DiPietro, J. A. Rough and tumble play: A function of gender. Dev Psychol, 17:50–58, 1981.CrossRefGoogle Scholar
  68. Döhler, K. D. Is female sexual differentiation hormone-mediated? Trends Neurosci 1: 138–140, 1978.CrossRefGoogle Scholar
  69. Döhler, K. D., Srivastava, S. S., Gorski, R. A., & Shryne, J. Postnatal tamoxifen treatment interfers with differentiation of the sexually dimorphic nucleus in both male and female rats. Endocrinology, 108:(Suppl), 204, 1981. (Abstract)Google Scholar
  70. Dorfman, R. I. The antiestrogenic and antiandrogenic activities of progesterone in the defence of a normal fetus. Anat Rec, 157:547–558, 1967.PubMedCrossRefGoogle Scholar
  71. Dorfman, R. I., & Dorfman, A. S. A test for anti-androgens. Acta Endocrinol, 33:308, 1960.PubMedGoogle Scholar
  72. Dorfman, R. I., & Kind, F. A. A new function of progesterone. IV. Reunion Anual, Sociedad Mexicana Nutricion y Endocrinologia, 171, 1963.Google Scholar
  73. Dörner, G., & Staudt, J. Structural changes in the preoptic anterior hypothalamic area of the male rat, following neonatal castration and androgen substitution. Neuroendocrinology, 3:136–140, 1965Google Scholar
  74. Dörner, G., & Staudt, J. Structural changes in the hypothalamic ventromedial nucleus of the male rat, following neonatal castration and androgen treatment. Neuroendocrinology, 4:278–281, 1968. (a)Google Scholar
  75. Dörner, G., & Staudt, J. Perinatal structural sex differentiation of the hypothalamus in rats. Neuroendocrinology, 5:103–106, 1969. (b)PubMedCrossRefGoogle Scholar
  76. Eaton, W. O., & von Bargen, D. Asynchronous development of gender understanding in preschool children. Child Dev, 52:1020–1027, 1981.CrossRefGoogle Scholar
  77. Edelstein, E. L. Psychodynamics of a transvestite. Am J Psychother, 14:121–131, 1960.PubMedGoogle Scholar
  78. Ehrhardt, A. A., & Baker, S. W. Males and females with congenital adrenal hyperplasia: A family study of intelligence and gender-related behavior. In P. A. Lee, L. P. Plotnick, A. A. Kowarski, and C. J. Migeon (Eds.): Congenital Adrenal Hyperplasia. Baltimore: University Park Press, 1977.Google Scholar
  79. Ehrhardt, A. A., & Money, J. Progestin-induced hermaphroditism: IQ and psychosexual identity in a study of ten girls. J Sex Res, 3:83–100, 1967.CrossRefGoogle Scholar
  80. Ehrhardt, A. A., Epstein, R., & Money, J. Fetal androgens and female gender identity in the early- treated andrenogenital syndrome. Johns Hopkins Med J, 122:160–167, 1968.PubMedGoogle Scholar
  81. Ehrhardt, A. A., Grisanti, G. C., & Meyer-Bahlburg, H. F. L. Prenatal exposure to medroxyprogesterone actetate (MPA) in girls. Psychoneuroendocrinology, 2:391–398, 1977.PubMedCrossRefGoogle Scholar
  82. Eil, C., Loriaux, D. L., & Schulman, J. D. Androgen resistance and sexual ambiguity.Contemp Ob/Gyn, 17:141–150, 1981.Google Scholar
  83. Ellis, A. The sexual psychology of human hermaphrodites. Psychosom Med, 7:108–125, 1945.Google Scholar
  84. Ellis, H. Studies in the Psychology of Sex. New York: Random House, 1936. (Originally published 1904.)Google Scholar
  85. Emery, D. E., & Sachs, B. D. Ejaculatory pattern in female rats without androgen treatment. Science, 190:484–486, 1975.PubMedCrossRefGoogle Scholar
  86. Epstein, A. W. Fetishism: A study of its psychopathology with particular reference to a proposed disorder in brain mechanisms as an etiological factor. J Nerv Ment Dis, 130:107–119, 1960.PubMedCrossRefGoogle Scholar
  87. Epstein, A. W. Relationship of fetishism and transvestism to brain and particularly to temporal lobe dysfunction. J Nerv Ment Dis, 133:247–253, 1961.PubMedCrossRefGoogle Scholar
  88. Fagot, B. I. The influence of sex of child on parental reactions to toddler children. Child Dev, 49:459–465, 1978.CrossRefGoogle Scholar
  89. Feder, H. H. The comparative actions of testosterone propionate and 5a-androstan-17ß-ol-3-one propionate on the reproductive behaviour, physiology and morphology of male rats. J Endocrinol, 51:241–252, 1971.PubMedCrossRefGoogle Scholar
  90. Feder, H. H., & Whalen, R. E. Feminine behavior in neonatally castrated and estrogen-treated male rats. Science, 147:306–307, 1965.CrossRefGoogle Scholar
  91. Ferenczi, S. Zur Nosologie der männlichen Homosexualität. Bausteine zur Psychoanalyse. Leipzig: Internationaler Psychoanalytischer Verlag, 1:152–170, 1927. (Originally published 1911.)Google Scholar
  92. Fischette, C. T., Biegon, A., & McEwen, B. S. Sex differences in serotonin 1 receptor binding in rat brain. Science, 222:333–335, 1983.PubMedCrossRefGoogle Scholar
  93. Fränkel, H. Homo mollis. Med Ztg, 22:102–103, 1853.Google Scholar
  94. Freund, K. A laboratory differential diagnosis of homo and heterosexuality—an experiment with faking. Revcz. Med, 7:20–31, 1961.Google Scholar
  95. Freund, K. Homosexualita u muzu [Homosexuality in man]. Praha: Statni zdrav nakl, 1962.Google Scholar
  96. Freund, K. Die Homosexualität heim Mann [Homosexuality in man]. 1st ed. Leipzig: Hirzel, 1963.Google Scholar
  97. Freund, K. Die Homosexualität beim Mann [Homosexuality in man]. 2nd ed. Leipzig: Hirzel, 1965.Google Scholar
  98. Freund, K. Male homosexuality: An analysis of the pattern. In J. A. Loraine (Ed.): Understanding Homosexuality: Its Biological and Psychological Bases. Lancaster: Medical and Technical Publishing, 1974.Google Scholar
  99. Freund, K. A conceptual framework for the study of anomalous erotic preferences. J Sex Marital Ther, 4:3–10, 1978.PubMedCrossRefGoogle Scholar
  100. Freund, K. Assessment of pedophilia. In M. Cook and K. Howells (Eds.): Adult Sexual Interest in Children. London: Academic Press, 1981.Google Scholar
  101. Freund, K., & Blanchard, R. Is the distant relationship of fathers and homosexual sons related to the sons’ erotic preference for male partners, or to the sons’ atypical gender identity, or to both? J Homosex, 9:7–25, 1983.PubMedCrossRefGoogle Scholar
  102. Freund, K., Nagler, E., Langevin, R., Zajac, A., & Steiner, B. W. Measuring feminine gender identity in homosexual males. Arch Sex Behav, 3:249–260, 1974.PubMedCrossRefGoogle Scholar
  103. Freund, K., Langevin, R., Satterberg, J., & Steiner, B. W. Extension of the Gender Identity Scale for males. Arch Sex Behav, 6:507–519, 1977.PubMedCrossRefGoogle Scholar
  104. Freund, K., & Pinkava, V. K otazce femininity u homosexualm’ch muzu. Cesk Psychiat, 56: 386–394, 1960.PubMedGoogle Scholar
  105. Freund, K., Scher, H., Chan, S., & Ben-Aron, M. Experimental analysis of pedophilia. Behav Res Ther, 20:105–112, 1982. (b)PubMedCrossRefGoogle Scholar
  106. Freund, K., Steiner, B. W., Chan, S. Two types of cross gender identity. Arch Sex Behav, 2:49–63, 1982. (a)CrossRefGoogle Scholar
  107. Gebhard, P. H., Gagnon, J. H., Pomeroy, W. B., and Christenson, C. B. Sex offenders. New York: Harper & Row, 1965.Google Scholar
  108. Gerall, A. A. Hormonal factors influencing masculine behavior of female guinea pigs. J Camp Physiol Psychol, 62:355–360, 1966.Google Scholar
  109. Gerall, A. A., Dunlap, J. L., & Hendricks, S. E. Effect of ovarian secretions on female behavioral potentiality in the rat. J Comp Physiol Psychol, 82:449–465, 1973.PubMedCrossRefGoogle Scholar
  110. Gesell, A. The First Years of Life. New York: Harper, 1940.Google Scholar
  111. Gessa, G. L., & Tagliamonte, A. Role of brain serotonin and dopamine in male sexual behavior. In M. Sandler and G. L. Gessa (Eds.): Sexual Behavior—Pharmacology and Biochemistry. New York: Raven Press, 1975.Google Scholar
  112. Goldfoot, D. A., Feder, H. H., & Coy, R. W. Development of bisexuality in the male rat treated neonatally with androstenedione. J Comp Physiol Psychol, 67:41–45, 1969.PubMedCrossRefGoogle Scholar
  113. Goldfoot, D. A., & Wallen, K. Development of gender role behaviors in heterosexual and isosexual groups of infant rhesus monkeys. In D. J. Chivers & J. Herbert (Eds.): Recent Advances in Primatology (Vol. 1). New York: Academic Press, 1978.Google Scholar
  114. Goodenough, F. L. Inter-relationships in the behavior of young children. Child Dev, 1:29–47, 1930.CrossRefGoogle Scholar
  115. Gooren, L. Aromatization of testosterone to estradiol is not required for maintenance of sexual behavior in the human male. In Z. Hoch and H. I. Lief (Eds.): Sexology: Sexual Biology, Behaviour and Therapy. Amsterdam: Excerpta Medica, 1982.Google Scholar
  116. Gorski, R. A. The neuroendocrinology of reproduction: An overview. Biol Reprod, 20:111–127, 1979.PubMedGoogle Scholar
  117. Gorski, R. A., Gordon, J. H., Shryne, J. E., & Southam, A. M. Evidence for a morphological sex difference within the medial preoptic area of the rat brain. Brain Res, 148:333–346, 1978.PubMedCrossRefGoogle Scholar
  118. Gorski, R. A., & Shryne, J. Intracerebral antibiotics and androgenization of the neonatal female rat. Neuroendocrinology, 10:109–120, 1972.PubMedCrossRefGoogle Scholar
  119. Gorski, R., Shryne, J., Gordon, J., & Christensen, L. Evidence for a morphological sex difference within the medial preoptic area (MPOA) of the rat. Anat Rec, 187:591, 1977.Google Scholar
  120. Goy, R. W., Bridson, W. E., & Young, W. C. Period of maximal susceptibility of the prenatal female guinea pig to masculinizing actions of testosterone propionate. J Comp Physiol Psychol, 57:166–174, 1964.PubMedCrossRefGoogle Scholar
  121. Goy, R. W., & Goldfoot, D. A. Neuroendocrinology: Animal models and problems of human sexuality. Arch Sex Behav, 4:405–420, 1975.PubMedCrossRefGoogle Scholar
  122. Goy, R. W., & McEwen, B. S. Sexual Differentiation of the Brain. Cambridge: M.I.T. Press, 1980.Google Scholar
  123. Goy, R. W., Wolf, J. E., & Eisele, S. Experimental female hermaphroditism in rhesus monkeys: Anatomical and psychological characteristics. In J. Money and H. Musaph (Eds.): Handbook of Sexology. Amsterdam: Excerpta Medica, 1977.Google Scholar
  124. Grady, K. L., Phoenix, C. H., & Young, W. C. Role of the developing rat testis in differentiation of the neural tissues mediating mating behavior. J Comp Physiol Psychol, 59:176–182, 1965.PubMedCrossRefGoogle Scholar
  125. Greenough, W. T., Carter, C. S., Steerman, C., & Devoogd, T. J. Sex difference in dendritic patterns in hamster preoptic area. Brain Research, 126:63–72, 1977.PubMedCrossRefGoogle Scholar
  126. Griffin, J. E. Testicular feminization associated with a thermolabile androgen receptor in cultured human fibroblasts. J Clin Invest, 64:1624–1631, 1979.PubMedCrossRefGoogle Scholar
  127. Griffin, J. E., & Wilson, J. D. The syndromes of androgen resistance. New Engl J Med, 302:198–209, 1980.PubMedCrossRefGoogle Scholar
  128. Gurney, M. E., & Konishi, M. A cellular analysis of androgen and estrogen induced sexual differentiation in the zebra finch song system. Soc Neurosci (Abstract), 5:446, 1979.Google Scholar
  129. Gutheil, E. Analysis of a case of transvestism. In W. Stekel (Ed.):Sexual Aberrations. New York: Liverwright, 1930.Google Scholar
  130. Hagemenas, F. G., & Kittinger, G. W. The influence of fetal sex on plasma progesterone levels. Endocrinology, 91:253–256, 1972.PubMedCrossRefGoogle Scholar
  131. Hamburger, G., & Stiirup, G. K. Transvestism: Hormonal, psychiatric, and surgical treatment. J Am Med Assoc, 152:391–396, 1953.PubMedCrossRefGoogle Scholar
  132. Hamilton, J. B., & Gardner, W. U. Effects in female young born of pregnant rats injected with androgens.Proc Soc Exp Biol Med, 37:570–572, 1938.Google Scholar
  133. Hampson, J. L., & Hampson, J. G. The ontogenesis of sexual behavior in man. In W. G. Young (Ed.): Sex and Internal Secretions. Baltimore: Williams & Wilkins, 1961.Google Scholar
  134. Hancke, J. L., & Döhler, K. D. Postnatal estradiol treatment prevents tamoxifen-induced de- feminization of the female rat brain. Acta Endocrinol (Supp), 94:102–102, 1980.Google Scholar
  135. Hadow, H. F. Sexual behavior in the rhesus monkey. In F. A. Beach (Ed.): Sex and Behavior. New York: John Wiley, 1965.Google Scholar
  136. Harris, G. W. Sex hormones, brain development and brain function. Endocrinology, 75:627–648, 1964.PubMedCrossRefGoogle Scholar
  137. Harris, G. W., & Levine, S. Sexual differentiation of the brain and its experimental control. J Physiol, 163:42P-43P, 1962.Google Scholar
  138. Harris, G. W., & Michael, R. P. The activation of sexual behaviour by hypothalamic implants of oestrogen. Physiol, 171:275–301, 1964.Google Scholar
  139. Harry, J. Defeminization and adult psychological well-being among male homosexuals. Arch Sex Behav, 12:l-19, 1983.CrossRefGoogle Scholar
  140. Hart, B. L. Manipulation of neonatal androgen: Effects on sexual responses and penile development in male rats. Physiol Behav, 8:841–845, 1972.PubMedCrossRefGoogle Scholar
  141. Hart, B. L. Gonadal androgen and sociosexual behavior of male mammals: A comparative analysis. Psychol Bull, 81:383–400, 1974.PubMedCrossRefGoogle Scholar
  142. Hart, B. L. Neonatal dihydrotestosterone and estrogen stimulation: Effect on sexual behavior of male rats. Horm Behav, 8:193–200, 1977.PubMedCrossRefGoogle Scholar
  143. Hart, B. L. Brain involvement in male sexual behavior. In Z. Hoch and I. Lief (Eds.): Sexology: Sexual Biology Behavior and Therapy. Amsterdam: Excerpta Medica, 1982.Google Scholar
  144. Hart, G. L., Haugen, G. M., & Peterson, D. M. Effects of medial preoptic-anterior hypothalamic lesions on mating behavior of male cats. Brain Res, 54:177–191, 1973.PubMedCrossRefGoogle Scholar
  145. Hastings, D. W. Postsurgical adjustment of male transsexual patients. Clin Plast Surg, 2:335–344, 1974.Google Scholar
  146. Hattwick, L. A. Sex differences in behavior of nursery school children. Child Dev, 8:343–355, 1937.CrossRefGoogle Scholar
  147. Hirschfeld, M. Die Transvestiten. Bedin: Alfred Pulvermacher, 1910.Google Scholar
  148. Hirschfeld, M. Die Homosexualität des Mannes und des Weibes, 2nd ed. Bedin: Marcus, 1920. (Originally published 1914.)Google Scholar
  149. Hirschfeld, M. Der Transvestitismus. In Sexualpathologie. Bonn: Marcus & Weber, 1922.Google Scholar
  150. Hoenig, J., & Duggan, E. Sexual and other abnormalities in the family of a transsexual. Psychiatr Clin, 7:334–346, 1974.Google Scholar
  151. Hore, B. D., Nicolle, F. V., & Calnan, J. S. Male transsexualism: Two cases in a single family. Arch Sex Behav, 2:317–321, 1973.PubMedCrossRefGoogle Scholar
  152. Hu, C. K., & Frazier, C. N. Masculinization of adult female rabbit following injection of testosterone propionate. Proc Soc Exp Biol Med, 42:820–823, 1940.Google Scholar
  153. Hunter, R., Logue, V., & McMenemy, W. H. Temporal lobe epilepsy supervening on longstanding transvestism and fetishism. A case report. Epilepsia, 4:40–65, 1963.Google Scholar
  154. Hutt, C. Males and Females: SeXY, SeXX. London: Penguin Education, 1975.Google Scholar
  155. Hyde, C., & Kenna, J. C. A male MZ twin pair, concordant for transsexualism, discordant for schizophrenia. Acta Psychiatr Scand, 56:265–273, 1977.PubMedCrossRefGoogle Scholar
  156. Imperato-McGinley, J., Guerrero, L., Gautier, T., & Petersen, R. E. Steroid 5a-reductase deficiency in man: An inherited form of male pseudohermaphroditism. Science, 186:1213–1215, 1974.PubMedCrossRefGoogle Scholar
  157. Imperato-McGinley, J., Peterson, R. E., Gautier, T., & Sturla, E. Male pseudohermaphroditism secondary to 5a-reductase deficiency—A model for the role of androgens in both the development of the male phenotype and the evolution of a male gender identity. J Steroid Biochem, 2:637–645, 1979. (a)CrossRefGoogle Scholar
  158. Imperato-McGinley, J., Peterson, R. E., Stoller, R., & Goodwin, W. E. Male pseudohermaphroditism secondary to 17ß-hydroxysteroid dehydrogenase deficiency: Gender role change with puberty. J Clin Endocrinol Metabol, 3:391–395, 1975.Google Scholar
  159. Imperato-McGinley, J., Peterson, R. E., Stoller, R., & Goodwin, W. E. Male pseudohermaphroditism secondary to 17ß-hydroxysteroid dehydrogenase deficiency: Gender role change with puberty. J Clin Endocrinol Metah, 49:391–394, 1979. (b)CrossRefGoogle Scholar
  160. Imperato-McGinley, J., Peterson, R. E., Gautier, T., & Sturla, E. Androgens and the evolution of male gender identity among male pseudohermaphrodites with 5a-reductase deficiency. New Engl J Med, 300:1233–1237, 1979. (c)PubMedCrossRefGoogle Scholar
  161. Imperato-McGinley, J., Peterson, R. E., Leshin, M., Griffin, J. E., Cooper, G., Draghi, S., Berenyi, M., & Wilson, J. D. Steroid 5 a-reductase deficiency in a 65-year-old male pseudohermaphrodite: The natural history, ultrastructure of the testes, and evidence for inherited enzyme heterogeneity. J Clin Endocrinol Metah, 50:15–22, 1980.CrossRefGoogle Scholar
  162. Jensen, E. V., and DeSombre, E. R. Estrogen-receptor interaction. Science, 182:126–134, 1973.PubMedCrossRefGoogle Scholar
  163. Johnson, W. A., & Tiefer, L. Sexual preferences in neonatally castrated male golden hamsters. Physiol Behav, 9:213–217, 1972.PubMedCrossRefGoogle Scholar
  164. Jones, N. Ethological studies of child behavior. London: Cambridge University Press, 1972.Google Scholar
  165. Jost, A. Recherches sur la differenciation sexuelle de Fembryon de lapin. (Troisieme partie: Role des gonades foetales dans la differenciation sexuelle somatique). Arch Anat Microsc Morphol Exp, 36:271–312, 1947. (a)Google Scholar
  166. Jost, A. Recherches sur la differenciation sexuelle de I’embryon de lapin. Arch Anat Microsc, 36:151–200, 1947. (b)Google Scholar
  167. Jost, A. Problems of fetal endocrinology: The gonadal and hypophyseal hormones.Recent Prog Horm Res, 8:379–413, 1953.Google Scholar
  168. Kallmann, F. J. Twin and sibship study of overt male homosexuality. Am J Hum Genet, 4:136–146, 1952. (a)PubMedGoogle Scholar
  169. Kallmann, F. J. Comparative twin study on the genetic aspects of male homosexuality. J Nerv Ment Dis, 115:283–298, 1952. (b)Google Scholar
  170. Karakiulakis, G., Knight, A., Powell, R., & Thomas, P. J. Sexual dimorphism in the number of dopamine receptors in limbic and non-limbic areas of rat brain. J Endocrinol, 79:32–33, 1979.Google Scholar
  171. Kester, P., Green, R., Finch, S. J., & Williams, K. Prenatal "female horihone" administration and psychosexual development in human males. Psychoneuroendocrinology, 5;269–285, 1980.PubMedCrossRefGoogle Scholar
  172. Kind, F. A., & Maqueo, M. Prevention by progesterone of steroid-induced sterility in neonatal male and female rats. Endocrinology, 77:859–862, 1965.CrossRefGoogle Scholar
  173. Kobayashi, F., & Gorski, R. A. Effects of antibiotics on androgenization of the neonatal female rat. Endocrinology, 86:285–289, 1970.PubMedCrossRefGoogle Scholar
  174. Kockott, G., & Nusselt, L. Zur Frage der cerebralen Dysfunktion bei der Transsexualität. Nervenarzt, 47:310–318, 1976.PubMedGoogle Scholar
  175. Koläfsky, A., Freund, K., Machek, J., & Poläk, O. Male sexual deviation: Association with early temporal lobe damage. Arch Gen Psychiatry, 17:735–743, 1967.CrossRefGoogle Scholar
  176. König, P. A. Genetische, endokrinologische und psychosexuelle Probleme bei testikulärer Feminisierung, Geburtshilfe Frauenheilk. Stuttgart: Georg Thieme Verlag, 20:166–180, 1960.Google Scholar
  177. Kono, S., Merriam, G. R., Brandon, D. D., Loriaux, D. L., & Lipsett, M. B. Radioimmunoassay and metabolism of the catechol estrogen 2-hydroxyestradiol. J Clin Endocrinol Metab, 54:150–154, 1982.Google Scholar
  178. Koo, G. G., Wachtel, S. S., Breg, W. R., & Miller, O. J. Mapping the locus of the H-Y antigen. Birth Defects, 12:175–177, 1976.PubMedGoogle Scholar
  179. Köster, R. Hormone factors in male behavior of the female rat. Endocrinology, 33:337–348, 1943.CrossRefGoogle Scholar
  180. Kraepelin, E. Psychiatrie. Leipzig: Barth, 1915.Google Scholar
  181. Kraepelin, E. Geschlechtliche Verirrungen und Volksvermehrung. Münch med Wsehr, 65:117–120, 1918.Google Scholar
  182. Krafft-Ebing, R. Psychopathia Sexualis. New York: Pioneer Publications, 1950. (Originally published 1886.)Google Scholar
  183. Krafft-Ebing, R. Psychopathia Sexualis (English Translation). New York: Stein & Day, 1965. (Originally published 1886.)Google Scholar
  184. Krafft-Ebing, R., & Moll, A. Psychopathia Sexualis. Stutgart: Enke, 1924.Google Scholar
  185. Kronfeld, A. Sexualpathologie. Leipzig-Wien: Deuticke, 1923.Google Scholar
  186. Krueger, D. W. Symptom passing in a transvestite father and three sons. Am J Psychiatry, 125:739–742, 1978.Google Scholar
  187. Ladosky, W., & Gaziri, L. G. J. Brain serotonin and sexual differentiation of the nervous system. Neuroendocrinology, 6:168–174, 1970.PubMedCrossRefGoogle Scholar
  188. LaFranchi, S., Magenis, E. R., & Prescott, G. H. Variation in pituitary-gonadal function in two adolescent boys with 46XX male syndrome. J Pediatr, 97:960–962, 1980.PubMedCrossRefGoogle Scholar
  189. Larsson, K. Features of the neuroendocrine regulation of masculine sexual behavior. In G. Beyer (Ed.): Endocrine Control of Sexual Behavior. New York: Raven Press, 1979.Google Scholar
  190. Larsson, K., & Södersten, P. Sexual behaviour in male rats treated with estrogen in combination with dihydrotestosterone. Horm Behav, 5:289–299, 1973.CrossRefGoogle Scholar
  191. Larsson, K., Södersten, P., & Beyer, G. Induction of male sexual behaviour by oestradiol benzoate in combination with dihydrotestosterone. J Endocrinology, 57:563–564, 1973.CrossRefGoogle Scholar
  192. Larsson, K., Södersten, P., Beyer, G., Morali, G., and Perez-Palacios, G. Effects of estrone, estradiol and estriol combined with dihydrotestosterone on mounting and lordosis behavior in castrated male rats. Horm Behav, 7:379–390, 1976.PubMedCrossRefGoogle Scholar
  193. Ledermair, O., and Delucca, A. Inkoplette testikuläre Feminisierung. Gynaecologia, J 68:49–54, 1968.Google Scholar
  194. Lee, P. A., Rock, J. A., Brown, T. R., Fichman, K. M., Migeon, G. J., & Jones, H. W. Leydigcell hypofunction resulting in male pseudohermaphroditism. Fertil Steril, 37:675–679, 1982.PubMedGoogle Scholar
  195. Leshin, M., Griffin, J. E., & Wilson, J. D. Hereditary male pseudohermaphroditism associated with an unstable form of 5 reductase. J Clin Invest, 62:685–681, 1978.PubMedCrossRefGoogle Scholar
  196. Levine, S., & Mullins, R., Jr. Estrogen administered neonatally affects adult sexual behavior in male and female rats. Science, 144:185–187, 1964.PubMedCrossRefGoogle Scholar
  197. Liakos, A. Familial transvestism. Br J Psychiatry, 113:49–51, 1967.PubMedCrossRefGoogle Scholar
  198. Lisk, R. D. Diencephalic placement of estradiol and sexual receptivity in the female rat.Am Physiol, 203:493–496, 1962.Google Scholar
  199. Lisk, R. D. Neural localization for androgen activation of copulatory behavior in the male rat. Endocrinology, 80:754–761, 1967.PubMedCrossRefGoogle Scholar
  200. Lisker, R., Flores, F., Cobo, A., & Rojas, F. G. A case of XX male syndrome. J Med Genet, 7:394–398, 1970.PubMedCrossRefGoogle Scholar
  201. Lloyd, T., & Weisz, J. Direct inhibition of tyrosine hydroxylase activity by catechol estrogens. J Biol Chem, 253:4841–4843, 1978.PubMedGoogle Scholar
  202. Luttge, W. G., & Hall, N. R. Differential effectiveness of testosterone and its metabolites in the induction of male sexual behavior in two strains of albino mice.Horm Behav, 4:31–43, 1973.CrossRefGoogle Scholar
  203. Maccoby, E. E. The Development of Sex Differences. Stanford: Stanford University Press, 1966.Google Scholar
  204. Maccoby, E. E., & Jacklin, C. N. The Psychology of Sex Differences. Stanford: Stanford University Press, 1974.Google Scholar
  205. Malmnäs, C. O., & Meyerson, B. J. p-Chlorophenylalanine and copulatory behaviour in the male rat. Nature, 232:388–400, 1971.CrossRefGoogle Scholar
  206. Martin, L. M. Transsexualism and homosexuality in a monozygotic twin pair. Paper presented at the 7th Int Gender Dysphoria Symp, Lake Tahoe, Nevada, 1981.Google Scholar
  207. Masica, D. N., Money, J., & Ehrhardt, A. A. Fetal feminization and female-gender identity in the testicular feminizing syndrome of androgen insensitivity. Arch Sex Behav, 1: 131–142, 1971.CrossRefGoogle Scholar
  208. Mau, H. Zum Einfluss von Testosterone auf Balz-, Kopulations- und aggressives Verhalten erwachsener weiblicher Stockenten. Jj, Diss Biolog Fak Univ München, 1973.Google Scholar
  209. McDonald, P., Beyer, C., Newton, F., Brien, B., Baker, R., Tan, H. S., Sampson, C., Kitching, P., Greenhill, R., & Pritchard, D. Failure of 5a-dihydrotestosterone to initiate sexual behaviour in the castrated male rat. Nature, 227:964–965, 1970.PubMedCrossRefGoogle Scholar
  210. McEwen, B. S. Neural gonadal steroid actions. Science, 211:1303–1311, 1981.PubMedCrossRefGoogle Scholar
  211. McKee, E. A., Robak, H. B., & Hollender, M. H. Transsexualism in two male triplets. Am J Psychiatry, 133:334–337, 1976.PubMedGoogle Scholar
  212. Meaney, M. J., Stewart, J., Poulin, P., & McEwen, B. S. Sexual differentiation of social play in rat pups is mediated by the neonatal androgen-receptor system. Neuroendocrinology, 37:85–90, 1983.PubMedCrossRefGoogle Scholar
  213. Meyer-Bahlburg, H. F. L. Sex hormones and male homosexuality in comparative perspective. Arch Sex Behav, 6:297–325, 1977.PubMedCrossRefGoogle Scholar
  214. Meyer-Bahlburg, H. F. L., Grisanti, G. C., & Ehrhardt, A. A. Prenatal effects of sex hormones on human male behavior: Medroxyprogesterone acetate (MPA). Psychoneuroendocrinology, 2:383–390, 1977.PubMedCrossRefGoogle Scholar
  215. Meyerson, B. Latency between intravenous injection of progestins and the appearance of estrous behavior in estrogen-treated ovariectomized rats. Horm Behav, 3:1–9, 1972.PubMedCrossRefGoogle Scholar
  216. Meyerson, G. J., Palis, A., & Sietnieks, A. Hormone-monoamine interactions and sexual behavior. In C. Beyer (Ed.): Endocrine Control of Sexual Behavior. New York: Raven Press, 1979.Google Scholar
  217. Michael, R. P. Oestrogens in the central nervous system. Br Med Bull, 21:87–90, 1965.PubMedGoogle Scholar
  218. Mitchell, W., Falconer, M. A., & Hill, D. Epilepsy with fetishism relieved by temporal lobectomy. Lancet 2, 267:626–630, 1954.CrossRefGoogle Scholar
  219. Mizejewski, G. J., Vonnegut, M., & Simon, R. Neonatal androgenization using antibodies to alpha-fetoprotein. Brain Res, 188:273–277, 1980.PubMedCrossRefGoogle Scholar
  220. Möhr, J. W., Turner, R. E., & Jerry, M. B. Pedophilia and Exhibitionism. Toronto: University of Toronto Press, 1964.Google Scholar
  221. Moll, A. Das Sexualleben des Kindes. Leipzig: Vogel, 1908.Google Scholar
  222. Money, J. Developmental differentiation of femininity and masculinity compared. In M. Färber & R. H. L. Wilson (Eds.): Man and Civilization: The Potential of Woman. New York: McGraw- Hill, 1963.Google Scholar
  223. Money, J. Sexual dimorphism and homosexual gender identity. Psychol Bull, 74:425–440, 1970.PubMedCrossRefGoogle Scholar
  224. Money, J., & Ehrhardt, A. A. Man and Woman, Boy and Girl. Baltimore: The Johns Hopkins University Press, 1972.Google Scholar
  225. Money, J., Ehrhardt, A. A., & Masica, D. N. Fetal feminization induced by androgen insensitivity in the testicular feminizing syndrome: Effect on marriage and maternalism. Johns Hopkins Med J, 123:105–114, 1968.PubMedGoogle Scholar
  226. Money, J., Hampson, G. J., & Hampson, J. L. An examination of some basic sexual concepts: The evidence of human hermaphroditism. Bull Johns Hopkins Hosp 97:301–319, 1955.PubMedGoogle Scholar
  227. Money, J., Hampson, J. G., & Hampson, J. L. Imprinting and the establishment of gender role. Arch Neurol Psychiatry, 77:333–336, 1957.Google Scholar
  228. Money, J., & Lewis, V. Homosexual/heterosexual status in boys at puberty: Idiopathic adolescent gynecomastia and congenital virilizing adrenocorticism compared. Psychoneuroendocrinology, 7:339–346, 1982.PubMedCrossRefGoogle Scholar
  229. Money, J., & Mathews, D. Prenatal exposure to virilizing progestins: An adult follow-up study of twelve women. Arch Sex Behav, 1:73–83, 1982.CrossRefGoogle Scholar
  230. Money, J., & Schwartz, M. Dating, romantic and nonromantic friendships, and sexuality in 17 early-treated adrenogenital females, aged 16–25. In P. A. Lee, L. P. Plotnick, A. A. Kowarski, and C. J. Migeon (Eds.): Congenital Adrenal Hyperplasia. Baltimore: University Park Press, 1977.Google Scholar
  231. Morali, G., Larsson, K., & Beyer, C. Inhibition of testosterone-induced sexual behavior in the castrated male rat by aromatase blockers. Horm Behav, 9:203–213, 1977.PubMedCrossRefGoogle Scholar
  232. Nadler, R. D. Masculinization of female rats by intracranial implantation of androgen in infancy. J Comp Physiol Psychol, 66:157–167, 1968.PubMedCrossRefGoogle Scholar
  233. Naftolin, F., & Ryan, K. J. The metabolism of androgens in central neuroendocrine tissues. J Steroid Biochem, 6:993–997, 1975.PubMedCrossRefGoogle Scholar
  234. Nash, J., & Hayes, F. The parental relationships of male homosexuals: Some theoretical issues and a pilot study. Aust J Psychol, 17:35–43, 1965.CrossRefGoogle Scholar
  235. Nottebohm, F., & Arnold, A. P. Sexual dimorphism in vocal control areas of the songbird brain. Science, 194:211–213, 1976.PubMedCrossRefGoogle Scholar
  236. Ohno, S., Nagai, Y., & Ciccarese, S. Testicular cells lysostripped of H-Y antigen organize ovarian follicle-like aggregates. Cytogenet Cell Genet, 20:351–364, 1978.PubMedCrossRefGoogle Scholar
  237. Olsen, K. L. Induction of male mating behavior in androgen-insensitive (tfm) and normal (King- Holtzman) male rats: Effect of testosterone propionate estradiol benzoate, and dihydrotestoster- one. Horm Behav, 13:66–84, 1979.PubMedCrossRefGoogle Scholar
  238. Opitz, J. M., Simpson, J. L., Sarto, G. E., Summitt, R. L., New, M., & German, J. Pseudovaginal perineoscrotal hypospadias. Clin Genet, 3:1–26, 1971.CrossRefGoogle Scholar
  239. Parrott, R. F. Effects of 17ß-hydroxy-4-androsten-19-ol-3-one (19-hydroxytestosterone) and 5a- androstan-17ß-ol-3-one (dihydrotestosterone) on aspects of sexual behavior in castrated male rats. J Endocrinol, 61:105–115, 1974.PubMedCrossRefGoogle Scholar
  240. Parrott, R. F. Aromatizable and 5a-reduced androgens: Differentiation between central and peripheral effects on male rat sexual behaviour. Horm Behav, 7:99–108, 1975.Google Scholar
  241. Parrott, R. F. Homotypical sexual behavior in gonadectomized female and male rats treated with 5a-19-hydroxytestosterone: Comparison with related androgens. Horm Behav, 7:207–215, 1976.PubMedCrossRefGoogle Scholar
  242. Parvizi, N., & Naftolin, F. Effects of catechol estrogens on sexual differentiation in neonatal female rats. Psychoneuroendocrinology, 2:409–411, 1977.PubMedCrossRefGoogle Scholar
  243. Paup, D. G., Mennin, S. P., & Gorski, R. A. Androgen- and estrogen-induced copulatory behavior and inhibition of luteinizing hormone (LH) secretion in the male rat. Horm Behav, 6:35–46, 1975.PubMedCrossRefGoogle Scholar
  244. Perez-Palacios, G., Larsson, K., & Beyer, G. Biological significance of the metabolism of androgens in the central nervous system. J Steroid Biochem, 6:999–1006, 1975.PubMedCrossRefGoogle Scholar
  245. Perry, D. G., & Bussey, K. The social learning theory of sex differences: Imitation is alive and well.J Pers Soc Psychol, 37:1699–1712, 1979.CrossRefGoogle Scholar
  246. Person, E., &Ovesey, L. Transvestism: New perspectives. J Am Acad Psychoanal, 6:301–323, 1978.PubMedGoogle Scholar
  247. Peterson, R. E., Imperato-McGinley, J., Gautier, T., & Sturla, E. Male pseudohermaphroditism due to steroid 5a-reductase deficiency. Am J Med, 62:170–191, 1977.PubMedCrossRefGoogle Scholar
  248. Petritzer, B. K., & Foster, J. A case study of a male transvestite with epilepsy and juvenile diabetes. J NervMentDis, 121:557–563, 1955.Google Scholar
  249. Pfaff, D. W. Morphological changes in the brains of adult male rats after neonatal castration. J Endocrinol, 36:415–416, 1966.PubMedCrossRefGoogle Scholar
  250. Pfaff, D. W., & McEwen, B. S. Actions of estrogens and progestins on nerve cells. Science, 219:333–335, 1983.CrossRefGoogle Scholar
  251. Pfaff, D. W., & Zigmond, R. E. Neonatal androgen effects on sexual and nonsexual behavior of adult rats tested under hormone regimes. Neuroendocrinology, 7:129–145, 1971.PubMedCrossRefGoogle Scholar
  252. Phoenix, C. H. Effects of dihydrotestosterone on sexual behavior of castrated male rhesus monkeys. Physiol Behav, 12:1045–1055, 1974.PubMedCrossRefGoogle Scholar
  253. Phoenix, C. H. Steroids and sexual behavior in castrated male rhesus monkeys. Horm Behav, 10:1–9, 1978.CrossRefGoogle Scholar
  254. Phoenix, C., Goy, R. W., Gerall, A. A., & Young, W. C. Organizing action of prenatally administered testosterone propionate on the tissues mediating mating behavior in the female guinea pig. Endocrinology, 65:369–382, 1959.PubMedCrossRefGoogle Scholar
  255. Phoenix, C. H., Jensen, J. N., & Chambers, K. C. Female sexual behavior displayed by an- drogenized female rhesus macaques. Horm Behav, 17:146–151, 1983.PubMedCrossRefGoogle Scholar
  256. Pillard, R. C., Poumadere, J., & Carretta, R. A. A family study of sexual orientation. Arch Sex Behav, 11: 511–520, 1982.PubMedCrossRefGoogle Scholar
  257. Polani, P. E., & Adinolfi, M. The H-Y antigen and its functions: A review and a hypothesis. J Immunogenet, 10:85–102, 1983.PubMedCrossRefGoogle Scholar
  258. Quadagno, D. M., & Ho, G. K. W. The reversible inhibition of steroid-induced sexual behavior by intracranial cycloheximide. Horm Behav, 6:19–26, 1975.PubMedCrossRefGoogle Scholar
  259. Quadagno, D. M., Shryne, J., & Gorski, R. A. The inhibition of steroid-induced sexual behavior by intrahypothalamic actinomycin D. Horm Behav, 2:1–10, 1971.CrossRefGoogle Scholar
  260. Radke, M. J. The Relation of Parental Authority to Children’s Behavior and Attitudes.Minneapolis: University of Minnesota Press, 1946.Google Scholar
  261. Rainbow, T. C., Davis, P. G., & McEwen, B. S. Anisomycin inhibits the activation of sexual behavior by estradiol and progesterone. Brain Res, 194:548–555, 1980.PubMedCrossRefGoogle Scholar
  262. Rainbow, T. C., Parsons, B., & McEwen, B. S. Sex differences in rat brain oestrogen and progestin receptors. Nature, 300:648–649, 1983.CrossRefGoogle Scholar
  263. Raisman, G., & Field, P. M. Sexual dimorphism in the preoptic area of the rat. Science, J 73:731–733, 1971.Google Scholar
  264. Raisman, G., & Field, P. M. Sexual dimorphism in the neuropil of the preoptic area of the rat and its dependence on neonatal androgen. Brain Res, 54:1–29, 1973.PubMedCrossRefGoogle Scholar
  265. Randell, J. Indications for sex reassignment surgery. Arch Sex Behav, 1:153–161, 1971.CrossRefGoogle Scholar
  266. Randell, J. B. Transvestism and transsexualism. A study of 50 cases. Br J Med, 2:1448–1452, 1959.CrossRefGoogle Scholar
  267. Raynaud, A. Comportement sexuel des souris femelles intersexuelles. Soc Biol, 1:993–995, 1938.Google Scholar
  268. Raynaud, A., and Frilley, M. Destruction des glandes genitales de Tembryon de souris, par une irradiation au moyen des rayons X, a Tage de treize jours. Ann Endocrinol, 8:400–419, 1947.Google Scholar
  269. Reinisch, J. M., & Karow, W. G. Prenatal exposure to synthetic progestins and estrogens: Effects on human development. Arch Sex Behav, 6:257–288, 1977.Google Scholar
  270. Rodriguez-Sierra, J. F., & Terasawa, E. Lesions of the preoptic area facilitates lordosis behavior in male and female guinea pigs. Brain Res Bull, 4:513–517, 1979.PubMedCrossRefGoogle Scholar
  271. Rubin, R. T., Reinisch, J. M., & Haskett, R. F. Postnatal gonadal steroid effects on human behavior. Science, 211:1318–1324, 1981.PubMedCrossRefGoogle Scholar
  272. Sabalis, R. F., Frances, A., Appenzeller, S. N., & Moseley, B. The three sisters: Transsexual male siblings. Am J Psychiatry, 131: 907–909 1974.PubMedGoogle Scholar
  273. Saenger, P., Goldman, A. S., Levine, L. S., Korth-Schutz, S., Muecke, E. C., Katsumata, M., Doberne, Y., & New, M. I. Prepubertal diagnosis of steroid 5a-reductase deficiency. J Clin Endocrinol Metah, 46:627–634, 1978.CrossRefGoogle Scholar
  274. Salaman, D. F. The role of DNA, RNA and protein synthesis in sexual differentiation of the brain. In D. F. Swaab & J. P. Schade (Eds.):Integrative Hypothalamic Activity, Progress in Brain Research (Vol. 41). New York: Elsevier Scientific Publishing Company, 1974.Google Scholar
  275. Salaman, D. F., & Birkett, S. Androgen-induced sexual differentiation of the brain is blocked by inhibitors of DNA and RNA synthesis. Nature, 247:109–113, 1974.PubMedCrossRefGoogle Scholar
  276. Salfield, D. J. Juvenile fetishism. Rev Psychiat Infant, 24:183–188, 1957.Google Scholar
  277. Sawyer, C. H. Induction of estrus in the ovariectomized cat by local hypothalamic treatment with estrogen, knat Rec 145:280, 1963.Google Scholar
  278. Schutz, F. Der Einfluss von Testosteron auf die Partnerwahl bei geprägt aufgezogenen Stockentenweibchen: Nachweis latenter Sexualprägung [Latent sexual imprinting in female mallards made evident by testosterone]. Verh Dtsch Zool Ges, 67:339–344, 1975.Google Scholar
  279. Shapiro, B. H., Goldman, A. S., & Root, A. W. Prenatal interference with the onset of puberty, vaginal cyclicity and subsequent pregnancy in the female rat (37804). Proc Sac Exp Biol Med, 145:334–339, 1974.Google Scholar
  280. Shapiro, B. H., Goldman, A. S., Bongiovanni, A. M., & Marino, J. M. Neonatal progesterone and feminine sexual development. Nature, 264:795–796, 1976.PubMedCrossRefGoogle Scholar
  281. Sheridan, P. J. Androgen receptors in the brain: What are we measuring? Endocr Reviews, 4:171–178, 1983.CrossRefGoogle Scholar
  282. Sheridan, P. J. Unaromatized androgen is taken up by the neonatal rat brain: Two receptor systems for androgen. Dev Neurosci, 4:46–54, 1981.PubMedCrossRefGoogle Scholar
  283. Sheridan, P. J., Sar, M., & Stumpf, W. E. Interaction of exogenous steroids in the developing rat brain. Endocrinology, 95:1749–1753, 1974.PubMedCrossRefGoogle Scholar
  284. Sherman, J. A. Sex-Related Cognitive Differences: An Essay on Theory and Evidence. Springfield: Charles C Thomas, 1978.Google Scholar
  285. Slimp, J. C., Hart, B. L., & Goy, R. W. Heterosexual, autosexual and social behavior of adult male rhesus monkeys with medial preoptic-anterior hypothalamic lesions. Brain Res, 142:105–122, 1978.PubMedCrossRefGoogle Scholar
  286. Smith, D. K. Transsexualism, sex reassignment surgery, and the law. Cornell L Rev, 56:963–1009, 1971.Google Scholar
  287. Södersten, P. Estrogen-activated sexual behavior in male rats. Horm Behav, 4:247–256, 1973.CrossRefGoogle Scholar
  288. Soulairac, M. L. Etude experimentale des regulations hormononerveuses du comportement sexuel du rat male. Ann Endocrin, 24, suppl:1–98, 1963.Google Scholar
  289. Soulairac, A., and Soulairac, M. L. Effets de lesions hypothalamiques sur le comportement sexuel et le fractus genital du rat male. Ann Endocrinol, 17:731–745, 1956.Google Scholar
  290. Steinach, E. Geschlechtstrieb und echt sekundäre Geschlechtsmerkmale als Folge der innersekretorischen Funktion der Keimdrüsen. Zentralbl Physiol, 24:551–566, 1910.Google Scholar
  291. Steinach, E. Umstimmung des Geschlechtscharakters bei Säugetieren durch Austausch der Pubertätsdrüsen. Zentralbl Physiologie, 25:723–725, 1911.Google Scholar
  292. Steinach, E. Willkürliche Umwandlung von Säugetier-Männchen in Tiere mit ausgeprägt weiblichen Geschlechtscharakteren und weiblicher Psyche. Eine Untersuchung über die Funktion und Bedeutung der Pubertätsdrüsen. Pflugers Arch, 144:71–108, 1912.CrossRefGoogle Scholar
  293. Steinach, E. Pubertätsdrüsen und Zwitterbildung. Archiv für Entwicklungsmechanik, 46:307–332, 1916.CrossRefGoogle Scholar
  294. Stern, J. J. The neonatal castration, androstenedione, and mating behavior of the male rat. J Comp Physiol Psychol, 69:608–612, 1969.PubMedCrossRefGoogle Scholar
  295. Stoller, R. J. Sex and Gender. New York: Science House, 1968.Google Scholar
  296. Stoller, R. J. The term "transvestism." Arch Gen Psychiatry, 24:230–237, 1971.PubMedCrossRefGoogle Scholar
  297. Stoller, R. J. Transvestism in women. Arch Sex Behav, 2:99–105, 1982.CrossRefGoogle Scholar
  298. Stoller, R. J., & Baker, H. J. Two male transsexuals in one family. Arch Sex Behav, 2:323–328, 1973.PubMedCrossRefGoogle Scholar
  299. Stone, C. P. A note on feminine behavior in adult male rats. Am J Physiol, 68:39–41, 1924.Google Scholar
  300. Swanson, H. H., & Crossley, D. A. Sexual behavior in the golden hamster and its modification by neonatal administration of testosterone propionate. In N. Hamburgh & E. J. W. Barrington (Eds.): Hormones in Development. New York: Appleton-Century-Crofts, 1971.Google Scholar
  301. Taylor, A. J. W., and McLachlan, D. G. Clinical and physiological observations on transvestism. NZ Med J, 61:496–506, 1962.Google Scholar
  302. Taylor, A. J. W., & McLachlan, D. C. Further observations and comments on transvestism. NZ Med J, 62:S27-S29, 1963.Google Scholar
  303. Terkel, A. S., Shryne, J., & Gorski, R. A. Inhibition of estrogen facilitation of sexual behavior by the intracerebral infusion of actinomycin-D. Horm Behav, 4: 377–386, 1973.CrossRefGoogle Scholar
  304. Terman, L. M., & Tyler, L. E. Psychological sex differences. In L. Carmichael (Ed.):Manual of Child Psychology, 2nd ed. New York: John Wiley, 1954.Google Scholar
  305. Terman, L. M., Johnson, W. B., Kuznets, G., & McNemar, O. W. Psychological sex differences. In L. Carmichael (Ed.): Manual of Child Psychology. New York: John Wiley, 1946.Google Scholar
  306. Thomas, C. N., & Gerall, A. A. Effect of hour of operation on feminization of neonatally castrated male rats. Psychonomic Science, 16:19–20, 1969.Google Scholar
  307. Toran-Allerand, C. D. Gonadal hormones and brain development: Cellular aspects of sexual differentiation. Zoologist, 18:553–565, 1978.Google Scholar
  308. Toran-Allerand, C. D. Coexistence of a-fetoprotein, albumin and transferrin immunoreactivity in neurons of the developing mouse brain. Nature, 286:733–735, 1980.PubMedCrossRefGoogle Scholar
  309. Toran-Allerand, C. D. Gonadal steroids and brain development. Trends in Neurosciences, 4:118–121, 1981.Google Scholar
  310. Vener, A., & Snyder, C. The pre-school child’s awareness of anticipation of adult sex roles. Sociometry, 29:159–168, 1966.PubMedCrossRefGoogle Scholar
  311. Völkel, H. Geschlechtsbewusstsein. Geschlechtsrolle und sexuelle Orientierung. Psychiatr Neurol, 145:257–278, 1963.Google Scholar
  312. Wachtel, S. S. H-Y antigen and the genetics of sex determination. Science, 198:797–799, 1977.PubMedCrossRefGoogle Scholar
  313. Wachtel, S. S. The dysgenetic gonad: Aberrant testicular differentiahon. Bio Reprod, 22:1–8, 1980.CrossRefGoogle Scholar
  314. Wachtel, S. S., Koo, G. C., Breg, W. R., Elias, S., Boyse, E. A., & Miller, O. J. Expression of H- Y antigen in human males with two Y chromosomes. New Eng J Med, 293:1070–1072, 1975.PubMedCrossRefGoogle Scholar
  315. Wagenen, G. Van, & Hamilton, J. B. The experimental production of pseudohermaphroditism in the monkey. In Essays in Biology, in honor of Herbert M. Evans, written by his friends. Berkeley: University of California Press, 1943.Google Scholar
  316. Walinder, J. Transvestism, definition and evidence in favor of occasional derivation from cerebral dysfunction. Int J Neuropsychiatry, 1:567–573, 1965.PubMedGoogle Scholar
  317. Walinder, J. Incidence and sex ratio of transsexualism in Sweden. Br J Psychiatry, 119:195–196, 1971.PubMedCrossRefGoogle Scholar
  318. Walter, K., & Bräutigam, W. Transvestitismus bei Klinefelter-Syndrom. Schweiz med Wochenschr, 88:357–362, 1958.PubMedGoogle Scholar
  319. Ward, I. L. Differential effect of pre- and postnatal androgen on the sexual behavior of intact and spayed female rats. Horm Behav, 1:25–36, 1969.CrossRefGoogle Scholar
  320. Ward, I. L. Female sexual behavior in male rats treated prenatally with anti-androgen.Physiol Behav, 8:53–56, 1972.PubMedCrossRefGoogle Scholar
  321. Westphal, C. Die konträre Sexualempfmdung, Symptom eines neuropathischen (psychopathischen) Zustandes. Arch Psychiatry, 2:73–108, 1870.CrossRefGoogle Scholar
  322. Whalen, R. E. Hormone-induced changes in the organization of sexual behavior in the male rat. J Comp Physiol Psychol, 57:175–182, 1964.PubMedCrossRefGoogle Scholar
  323. Whalen, R. E. Sexual differentiation: Models, methods and mechanisms. In R. C. Friedman, R. M. Richart, & R. L. Vande Wiele (Eds.): Sex Differences in Behavior. New York: John Wiley, 1974.Google Scholar
  324. Whalen, R. E., Battie, C., & Luttge, W. G. Anti-estrogen inhibition of androgen-induced sexual receptivity in rats. Behav Biol, 7:311–320, 1972.PubMedCrossRefGoogle Scholar
  325. Whalen, R. E., & DeBold, J. F. Comparative effectiveness of testosterone androstenedione and dihydrotestosterone in maintaining mating behavior in the castrated male hamster. Endocrinology, 95:1674–1679, 1974.PubMedCrossRefGoogle Scholar
  326. Whalen, R. E., Edwards, D. A., Luttge, W. G., & Robertson, R. T. Early-ndrogen treatment and male sexual behavior in female rats. Physiol Behav, 4:33–39, 1969.CrossRefGoogle Scholar
  327. Whalen, R. E., Gorzalka, B. B., DeBold, J. F., Quadagno, D. M., Ho, G. K., & Hough, J. C., Jr. Studies on the effects of intracerebral actinomycin D implants on estrogen-induced receptivity in rats. Horm Behav, 5:337–343, 1974.PubMedCrossRefGoogle Scholar
  328. Whalen, R. E., & Luttge, W. G. Perinatal administration of dihydrotestosterone to female rats and the development of reproductive function. Endocrinology, 89:1320–1322, 1971.PubMedCrossRefGoogle Scholar
  329. Whalen, F. E., & Nadler, R. D. Suppression of the development of female mating behavior by estrogen administered in infancy. Science, 141:271–274, 1963.Google Scholar
  330. Whitam, F. L. Childhood indicators of male homosexuality. Arch Sex Behav, 6:89–96, 1977.PubMedCrossRefGoogle Scholar
  331. Wilson, J. D., George, F. W., & Griffin, J. E. The hormonal control of sexual development. Science, 211:1278–1284, 1981.PubMedCrossRefGoogle Scholar
  332. Wilson, J. D., Harrod, M. J., Goldstein, J. L., Hemsell, D. L., & MacDonald, P. G. Familial incomplete male pseudohermaphroditism. Type 1: Evidence for androgen resistance and variable clinical manifestations in a family with the Reifenstein syndrome. New Engl J Med, 290:1097–1103, 1974.PubMedCrossRefGoogle Scholar
  333. Witschi, E. Modification of the development of sex in lower vertebrates and in mammals. In E. Allen (Ed.): Sex and Internal Secretions, 2nd ed. Baltimore: Williams & Wilkins, 1939. (Originally published 1932.)Google Scholar
  334. Wittig, M. A., & Petersen, A. C. (Eds.) Sex-Related Differences in Cognitive Functioning. New York: Academic Press, 1979.Google Scholar
  335. Wolf, U., Fraccaro, M., Mayerova, A., Hecht, T., Zuffardi, O., & Hameister, H. Turner syndrome patients are H-Y positive. Hum Genet, 54:315–318, 1980.PubMedCrossRefGoogle Scholar
  336. Wolff, E. Recherches sur I’intersexualite experimentale produit par la methode des greffes de gonades ä Fembrion de poulet. Arch Anat Micro et Morphol Experimental, 41:69–90, 1946.Google Scholar
  337. Wolff, E., and Haffen, K. Sur Tintersexualite experimentale des gonades embryonnaires de canard, cultivees in vitro. Arch Anat Microsc Morphol Exp, 41:184–207, 1952.Google Scholar
  338. Wolff, E., and Wolff, E. The effects of castration on bird embryos. J Exptl Zool, 116:59–97, 1951.CrossRefGoogle Scholar
  339. Yalom, I. D., Green, R., & Fisk, N. Prenatal exposure to female hormones: Effect on psychosexual development in boys. Arch Gen Psychiatry, 28:554–561, 1973.PubMedCrossRefGoogle Scholar
  340. Yawger, N. S. Transvestism and other cross sex manifestations. J Nerv Ment Dis, 92:41–48, 1940.CrossRefGoogle Scholar
  341. Young, W. C. The hormones and mating behavior. In W. C. Young (Ed.): Sex and Internal Secretions. Baltimore: Williams & Wilkins, 1961.Google Scholar
  342. Züblin, W. Geschlechtschromosom, Geschlechtshormon und psychische Sexualität. Schweiz Z Psychol, 16:118–120, 1957.Google Scholar
  343. Zuger, B. Gender role determination: A critical review of the evidence from hermaphroditism. Psychosom Med, 32:449–467, 1970.PubMedGoogle Scholar
  344. Zuger, B. Effeminate behavior present in boys from childhood: Ten additional years of follow-up. Compr Psychiatry, 19:363–369, 1978.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Kurt Freund
    • 1
  1. 1.Department of Behavioural SexologyClarke Institute of PsychiatryTorontoCanada

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