• Forrest H. Nielsen
  • Eric O. Uthus
Part of the Biochemistry of the Elements book series (BOTE, volume 3)


Since ancient times, arsenicals have been characterized by actions both benevolent and malevolent. The sulfides of arsenic—realgar (tetraarsenic tetrasulfide) and orpiment (arsenic trisulfide)—were mentioned by the Greeks and Romans prior to the Christian era. However, pure arsenic apparently was unknown to these ancient civilizations. Because arsenic has such a long history, only a few highlights will be presented here. These highlights were obtained from reviews by Vallee et al. (1960), Schroeder and Balassa (1966), Frost (1970), Klevay (1976), and Bruckner and Dietze (1980).


Zinc Deficiency Inorganic Arsenic Arsenic Trioxide Arsenic Compound Dimethylarsinic Acid 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Forrest H. Nielsen
    • 1
    • 2
  • Eric O. Uthus
    • 1
    • 2
  1. 1.Agricultural Research Service, Grand Forks Human Nutrition Research CenterU.S. Department of AgricultureGrand ForksUSA
  2. 2.Department of BiochemistryUniversity of North DakotaGrand ForksUSA

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