Although interest in the silicon content of animal tissues and the effect of siliceous substances on animals was expressed over half a century ago (King and Belt, 1938), emphasis has been placed until recently on the toxicity of silicon, mainly its involvement in silicosis. The occurrence of silicon in living systems, its physiological and biochemical roles, and its toxicology have attracted increasing research interest over the last 10 years (for an extensive review, see Bendz and Lindquist, 1978) because it is only within the last decade that silicon has been recognized as participating in the normal metabolism of higher animals and as an essential trace element. Silicon has been shown to be required in bone, cartilage, and connective tissue formation as well as participating in several other important metabolic processes.


Hyaluronic Acid Silicic Acid Silicon Content Urinary Calculus Silicon Compound 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Edith Muriel Carlisle
    • 1
  1. 1.Division of Nutrition, School of Public HealthUniversity of CaliforniaLos AngelesUSA

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