Chromosomal Defects and Their Role in Lymphomagenesis

  • Avery A. Sandberg


The major thrust of this book, i.e., lymphoproliferative disorders in subjects rendered immunodeficient either through therapy or inheritance and, thus, more susceptible to infections with viruses (particularly Epstein-Barr virus, EBV), raises a number of crucial questions regarding the role of chromosomal changes at various stages of these complex events. An attempt will be made to relate known cytogenetic events and changes in lymphoma to their possible role in lymphomagenesis in immune deficiency disorders. The terms cytogenetic, chromosomal and karyotypic will be used interchangeably.


Chronic Lymphocytic Leukemia Sister Chromatid Exchange Infectious Mononucleosis Ataxia Telangiectasia Ataxia Telangiectasia 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Avery A. Sandberg
    • 1
  1. 1.Roswell Park Memorial InstituteBuffaloUSA

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