Biology of Epstein-Barr Virus

  • Hans Wolf


Epstein-Barr virus (EBV) has been linked to infectious mononucleosis and to the neoplasias, nasopharyngeal carcinoma and Burkitt’s lymphoma. The initial evidence of an etiologic relationship was mainly derived from seroepidemiological studies (for review see ref. 1) and confirmed by nucleic acid hybridization with biopsy materials (for review see ref. 2). The work of many laboratories contributed data which does not seem to fit into a unifying concept. This paper briefly summarizes some apparently conflicting results; from these data a hypothetical model for the biology of EBV is developed.


Nasopharyngeal Carcinoma Lymphoblastoid Cell Line Infectious Mononucleosis Lytic Cycle Early Antigen 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Hans Wolf
    • 1
  1. 1.Max von Pettenkofer Institute of Hygiene and MicrobiologyUniversity of MunichMunichWest Germany

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