Advertisement

Phase I Trial Using Thymosin Fraction 5 in Renal Cancer

Northern California Oncology Group (NCOG) Report
  • William M. Wara
  • Marguerite H. Neely
  • Linda J. Fippin
  • Diane W. Wara
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

A number of laboratories have now isolated and purified thymic hormone-like factors from animal tissues and blood. These thymic hormones may have the potential to mature precursor lymphocytes to adult functioning cells. This effect could be advantageous for cancer patients to reverse the immunosuppressive effects of chemotherapy, radiotherapy, surgery, and of the tumor itself (W. Wara et al., 1975).

Keywords

Renal Cell Carcinoma Brain Metastasis Small Cell Carcinoma Renal Cell Carcinoma Patient Thymic Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Chretien, P. B., Lipson, S. D., Makuck, R., Kenady, D. E., Cohen, M. H., and Minna, J. D., 1978, Thymosin in cancer patients—In vitro effects: Correlations with clinical response to thymosin immunotherapy, Cancer Treat. Rep. 62:1787.PubMedGoogle Scholar
  2. Wara, D. W., and Ammann, A. J., 1978, Thymosin treatment of children with primary immunodeficiency disease, Transplant. Proc. 10:203–208.PubMedGoogle Scholar
  3. Wara, D. W., Goldstein, A. L., Doyle, N. E., and Ammann, A. J., 1975, Thymosin activity in patients with cellular immunodeficiency, N. Engl. J. Med. 292:70–74.PubMedCrossRefGoogle Scholar
  4. Wara, W. M., Phillips, T. L., Wara, D. W., Ammann, A. J., and Smith, V., 1975, Immunosuppression following radiation therapy for carcinoma of nasopharynx, Am. J. Roentgenol. 123:482–485.Google Scholar
  5. Wara, W. M., Neely, M. H., Ammann, A. J., and Wara, D. W., 1981, Thymosin adjuvant therapy in advanced head and neck cancer, in: Adjuvant Therapy of Cancer III (S. E. Salmon and S. E. Jones, eds.), pp. 169–173, Grune & Stratton, New York.Google Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • William M. Wara
    • 1
    • 2
  • Marguerite H. Neely
    • 3
  • Linda J. Fippin
    • 3
  • Diane W. Wara
    • 4
  1. 1.Department of Radiation OncologyUniversity of CaliforniaSan FranciscoUSA
  2. 2.Northern California Cancer ProgramPalo AltoUSA
  3. 3.Department of Radiation OncologyUniversity of CaliforniaSan FranciscoUSA
  4. 4.Pediatric ImmunologyUniversity of CaliforniaSan FranciscoUSA

Personalised recommendations