Advertisement

The in Vivo Effect of Thymosin on Cell-Mediated Immunity

  • S. B. Salvin
  • Ruth Neta
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

Inbred strains of mice, similar to individual humans, vary in their resistance to infections. Variations also exist in the capacity of inbred strains of sensitized mice to release lymphokines into the circulation (Neta et al., 1981). As little evidence is present on the role of individual in vivo-induced lymphokines in resistance to infections, correlation of these variations in the different murine strains may lead to the development of a better experimental model in which to study their association. A possible presence in some strains of a defect in both resistance and the in vivo release of lymphokines, together with the means of corrective treatment of either or both parameters, will present a model in which such studies may be conducted.

Keywords

Candida Albicans Migration Inhibitory Factor Inbred Strain Susceptible Strain Thymic Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Neta, R., and Salvin, S. B., 1983, Resistance and susceptibility to infection in inbred murine strains. II. Variations in the effect of treatment with thymosin, Cell. Immunol. 75:173–180.PubMedCrossRefGoogle Scholar
  2. Neta, R., Salvin, S. B., and Sabaawi, M., 1981, Mechanisms in the in vivo release of lymphokines. I. Comparative kinetics in the release of six lymphokines in inbred strains of mice, Cell. Immunol. 64:203–219.PubMedCrossRefGoogle Scholar
  3. Salvin, S. B., and Neta, R., 1983, Resistance and susceptibility to infection in inbred murine strains. I. Variations in the response to thymic hormones in mice infected with Candida albicans, Cell. Immunol. 75:160–172.CrossRefGoogle Scholar
  4. Salvin, S. B., and Nishio, J., 1969, in vitro cell reactions in delayed hypersensitivity, J. Immunol. 103:138–141.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • S. B. Salvin
    • 1
  • Ruth Neta
    • 2
  1. 1.Department of Microbiology, School of MedicineUniversity of PittsburghPittsburghUSA
  2. 2.Armed Forces Radiobiology Research InstituteBethesdaUSA

Personalised recommendations