The in Vivo Effect of Thymosin on Cell-Mediated Immunity
Inbred strains of mice, similar to individual humans, vary in their resistance to infections. Variations also exist in the capacity of inbred strains of sensitized mice to release lymphokines into the circulation (Neta et al., 1981). As little evidence is present on the role of individual in vivo-induced lymphokines in resistance to infections, correlation of these variations in the different murine strains may lead to the development of a better experimental model in which to study their association. A possible presence in some strains of a defect in both resistance and the in vivo release of lymphokines, together with the means of corrective treatment of either or both parameters, will present a model in which such studies may be conducted.
KeywordsCandida Albicans Migration Inhibitory Factor Inbred Strain Susceptible Strain Thymic Hormone
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