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Efficacy of Thymosin α1 in Animal Models

  • Hideo Ishitsuka
  • Yukio Umeda
  • Emiko Tezuka
  • Yumiko Ohta
  • Yasuo Yagi
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

The thymus gland produces many factors which are known to play a major role in the differentiation and maturation of T cells (Trainin et al., 1983). Considering the importance of T cells in immunoregulatory systems, thymic factors are expected to be useful as pharmaceutical agents to counteract immunodeficiency states. Thymic factors have been given in many clinical instances and shown to improve immunodeficiency diseases, particularly those with congenital T-cell defects (Wara et al., 1975). However, their efficacy in patients with the secondary immunodeficiencies has not been fully investigated.

Keywords

Natural Killer Cell Bone Marrow Cell Spleen Cell Adoptive Transfer Recipient Mouse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Hideo Ishitsuka
    • 1
  • Yukio Umeda
    • 1
  • Emiko Tezuka
    • 1
  • Yumiko Ohta
    • 1
  • Yasuo Yagi
    • 1
  1. 1.Nippon Roche Research CenterKamakura City, Kanagawa 247Japan

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