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Use of Monoclonal Antibodies to Identify Antigens of Human Endocrine Thymic Epithelium

  • Barton F. Haynes
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

The thymus plays a central role in the differentiation of T lymphocytes (Cantor and Weissman, 1976). Lymphocytes in various stages of maturation are found throughout the thymic cortex and medulla; however, only a minority of thymic lymphocytes mature completely and migrate to peripheral lymphoid organs (Matsuyama et al., 1966; McPhee et al., 1979). Thymic epithelial cells are in intimate contact with thymic lymphocytes, are thought to promote normal intrathymic maturation, and contain thymic hormones such as thymopoietin and thymosin α1 (Bach and Goldstein, 1980).

Keywords

Acquire Immune Deficiency Syndrome Thymic Epithelial Cell Thymic Tissue Human Thymus Thymic Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Barton F. Haynes
    • 1
  1. 1.Department of Medicine, Division of Rheumatic and Genetic DiseasesDuke University School of MedicineDurhamUSA

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