Use of Monoclonal Antibodies to Identify Antigens of Human Endocrine Thymic Epithelium
The thymus plays a central role in the differentiation of T lymphocytes (Cantor and Weissman, 1976). Lymphocytes in various stages of maturation are found throughout the thymic cortex and medulla; however, only a minority of thymic lymphocytes mature completely and migrate to peripheral lymphoid organs (Matsuyama et al., 1966; McPhee et al., 1979). Thymic epithelial cells are in intimate contact with thymic lymphocytes, are thought to promote normal intrathymic maturation, and contain thymic hormones such as thymopoietin and thymosin α1 (Bach and Goldstein, 1980).
KeywordsAcquire Immune Deficiency Syndrome Thymic Epithelial Cell Thymic Tissue Human Thymus Thymic Hormone
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