Thymulin

New Biochemical Aspects
  • M. Dardenne
  • W. Savino
  • L. Gastinel
  • J.-F. Bach
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

The thymus gland produces numerous polypeptide hormones that can induce T-cell markers and functions in immature cells and, consequently, are considered to be physiologically involved in T-cell differentiation (Bach, 1979). One of these hormones, thymulin, formerly called FTS (for facteur thymique sérique), was initially isolated from porcine serum (Dardenne et al., 1977) but also purified from human serum. Its amino acid sequence was determined (Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn) (Pléau et al., 1977) and the synthetic peptide was shown to be fully biologically active (Bach et al., 1977).

Keywords

Zinc Filtration Albumin Polypeptide Neurol 

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References

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • M. Dardenne
    • 1
  • W. Savino
    • 1
  • L. Gastinel
    • 1
  • J.-F. Bach
    • 1
  1. 1.INSERM U-25Hôpital NeckerParisFrance

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