The studies in the early 1960s by Miller (Miller, 1961), and Good (Good et al., 1962) have established that the thymus is necessary for the normal development of the immune response. For the past 20 years, a large research effort has been directed toward the isolation and identification of the thymic factors or hormones responsible for the physiological functions of the thymus gland (Low and Goldstein, 1978). Our previous studies demonstrated that a partially purified bovine thymic preparation termed thymosin fraction 5 could partially or fully reconstitute immune functions in immunodeficient diseases, autoimmune diseases, and cancer.
KeywordsMixed Lymphocyte Reaction Minimal Change Nephrotic Syndrome Complete Amino Acid Sequence Thymic Hormone Polypeptide Component
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