Characterization of Immunoaffinity-Purified Human T-Cell Growth Factor from JURKAT Cells

  • Terry D. Copeland
  • Kendall A. Smith
  • Stephen Oroszlan
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


T-cell growth factor (TCGF) is a lymphokine that was first identified in conditioned media of mitogen-activated human T-cell culture (Morgan et al., 1976). TCGF also occurs in other mammalian systems and its biological properties were recently reviewed (Smith, 1983). TCGF proved to be essential for the isolation of human T-cell leukemia virus. For a recent review see Gallo and Wong-Staal (1982).


JURKAT Cell Bovine Leukemia Virus Intact Protein Acetonitrile Concentration Nucleic Acid Binding Protein 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Terry D. Copeland
    • 1
  • Kendall A. Smith
    • 2
  • Stephen Oroszlan
    • 1
  1. 1.Laboratory of Molecular Virology and Carcinogenesis, LBI-Basic Research ProgramNCI-Frederick Cancer Research FacilityFrederickUSA
  2. 2.Department of MedicineDartmouth Medical SchoolHanoverUSA

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