Production of a Thymosin α1-like Material by T-Cell Lymphomas

  • Marion M. Zatz
  • Paul H. Naylor
  • Allan L. Goldstein
  • John E. McClure
  • Barton F. Haynes
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


Thymosin α1 is a peptide (MW 3108) originally isolated from calf thymosin fraction 5, a partially purified preparation of bovine thymus (Low and Goldstein, 1979). It is believed to be one of the thymic hormones secreted by the thymic epithelium (Kater et al., 1979; Dalakas et al., 1981; Hirokawa et al., 1982; Haynes et al., 1983) and has known biological properties in inducing differentiation and maturation of T lymphocytes in experimental animal models as well as in man (Zatz et al., 1982).


Acquire Immune Deficiency Syndrome Thymic Hormone Thymic Epithelium IRal Level Bovine Thymus 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Marion M. Zatz
    • 1
  • Paul H. Naylor
    • 1
  • Allan L. Goldstein
    • 1
  • John E. McClure
    • 2
  • Barton F. Haynes
    • 3
  1. 1.Department of BiochemistryThe George Washington University School of Medicine and Health SciencesUSA
  2. 2.Allergy-Immunology Service, Department of PediatricsTexas Children’s HospitalHoustonUSA
  3. 3.Department of Medicine, Division of Rheumatic and Genetic DiseasesDuke University School of MedicineDurhamUSA

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