Human Peripheral Blood Lymphocytes Bear Markers for Thymosins (α1, α7, β4)
Within a partially purified calf thymic extract termed thymosin fraction 5 (Goldstein et al., 1972), there exist several active polypeptides with distinct immunobiological action (Trivers and Goldstein, 1980; Low and Goldstein, 1982). Among those, thymosin α1 affects the early stages of T-lymphocyte maturation and induces helper T cells; thymosin α7 affects the induction of suppressor T-cell development (Trivers and Goldstein, 1980); and thymosin β4 affects the maturation of prothymocytes and has a MIF-like activity (Low and Goldstein, 1982).
KeywordsPeripheral Blood Lymphocyte Normal Rabbit Serum Thymic Epithelial Cell Human Peripheral Blood Lymphocyte Human Thymus
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