Abstract
Herpes simplex viruses (HSVs) are among the most common infectious agents of man. There are two distinct serotypes (HSV-1 and HSV-2), and they usually have different modes of transmission. HSV1 is transmitted chiefly via a nongenital route, whereas HSV-2 is most often transmitted venereally or from a mother’s genital infection to the newborn. The mode of spread of each of the two virus types is reflected by its relative prevalence at different ages and by its pattern of clinical distribution within the host. Thus, HSV-1 infections occur most frequently during childhood and usually affect body sites above the waist. HSV-2 infections, on the other hand, occur most often during adolescence and young adulthood and involve body sites below the waist, primarily the genitals. Most infections in newborns are also caused by HSV-2.
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Suggested Readings
Juretic, M., Herpetic Infections of Man, University Press of New England, Hanover, New Hampshire, 1980
Kaplan, A. S. (ed.), The Herpesviruses, Academic Press, New York, 1973.
Nahmias, A., Dowdle, R., and Schinazi, R. (eds.), The Human Herpesviruses: An Interdisciplinary Perspective, Elsevier/North-Holland, New York, 1981.
Rapp, F. (ed.), Oncogenic Herpesviruses, Vol. 1 and 2, CRC Press, Boca Raton, Florida, 1980.
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Nahmias, A.J., Josey, W.E. (1984). Herpes Simplex Viruses 1 and 2. In: Evans, A.S. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4727-9_13
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