Time-Resolved Laser Fluorescence and Photobleaching of Single Cells after Photosensitization with Hematoporphyrin Derivative (HpD)
Because of its preferential retention in tumor cells hematopor-phyrin derivative (HpD) is used for diagnosis1,2 and phototherapy 3 of tumors. The cytotoxic effect has been attributed to the formation of singlet oxygen after intermolecular energy transfer HpD→O2 4 or to the production of HpD radicals 5.
KeywordsFluorescence Decay Curve Hematoporphyrin Derivative Human Urinary Bladder Preferential Retention Integral Fluorescence
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