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Time-Resolved Laser Fluorescence and Photobleaching of Single Cells after Photosensitization with Hematoporphyrin Derivative (HpD)

  • H. Schneckenburger
  • E. Unsöld
  • W. Weinsheimer
  • D. Jocham

Abstract

Because of its preferential retention in tumor cells hematopor-phyrin derivative (HpD) is used for diagnosis1,2 and phototherapy 3 of tumors. The cytotoxic effect has been attributed to the formation of singlet oxygen after intermolecular energy transfer HpD→O2 4 or to the production of HpD radicals 5.

Keywords

Fluorescence Decay Curve Hematoporphyrin Derivative Human Urinary Bladder Preferential Retention Integral Fluorescence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • H. Schneckenburger
    • 1
  • E. Unsöld
    • 1
  • W. Weinsheimer
    • 1
    • 2
  • D. Jocham
    • 1
    • 2
  1. 1.Abteilung f. Angewandte OptikGesellschaft f. Strahlen- und Umweltforschung mbH MünchenNeuherbergF.R. Germany
  2. 2.Urologische Klinik und PoliklinikKlinikum GroßhadernMünchen 70F.R.Germany

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