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Maturation of the Follicular Microenvironment

  • Cecilia L. Schmidt

Abstract

Over the past decade, the orchestration of the menstrual cycle, formerly attributed to the hypothalamic-pituitary axis, has been properly ascribed to the dominant follicle. It is the microenvironment of the follicle destined to ovulate that determines the circulating hormonal milieu and impinges upon the fate of the selected oocyte. The purpose of this chapter is to survey the factors basic to follicular development and achievement of dominance in the spontaneous menstrual cycle. Understanding these events is mandatory to those who attempt hormonal manipulation of the ovarian cycle to ensure oocyte retrieval for in vitro fertilization.

Keywords

Granulosa Cell Corpus Luteum Follicular Fluid Zona Pellucida Antral Follicle 
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© Plenum Press, New York 1984

Authors and Affiliations

  • Cecilia L. Schmidt

There are no affiliations available

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