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Virus Associated DNA Polymerizing Activities: Their Role in Designing Antiviral and Antitumor Agents

  • P. Chandra
  • I. Demirhan
  • U. Ebner
  • B. Kornhuber
Part of the NATO ASI Series book series (NSSA, volume 73)

Abstract

Inhibitors of nucleic acid biosynthesis have an honorable place in the history of chemotherapy. Nucleic acids, or nucleic acid polymerizing enzymes, have served as extremely useful targets in the development of chemotherapeutic agents to combat infectious and malignant diseases. In some cases, such as antiviral agents, this approach has provided virtually the only means to design effective chemotherapeutic compounds.

Keywords

Long Terminal Repeat Terminal Deoxynucleotidyl Transferase Reverse Transcriptase Reaction Viral Enzyme Polycytidylic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • P. Chandra
    • 1
  • I. Demirhan
    • 1
  • U. Ebner
    • 1
  • B. Kornhuber
    • 1
  1. 1.Center of Biological Chemistry (Lab. of Molecular Biology) and Dept. of Pediatric OncologyUniv. School of MedicineD-6 Frankfurt (Main) 70W. Germany

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