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Overview of the Possible Targets for Viral Chemotherapy

  • William H. Prusoff
  • Tai-Shun Lin
  • William R. Mancini
  • Michael J. Otto
  • Scott A. Siegel
  • J. J. Lee
Part of the NATO ASI Series book series (NSSA, volume 73)

Abstract

The ideal target for prevention of viral infections is eradication of either the virus or the host, since both are required to produce an infection. For a variety of reasons, mostly personal, we would all agree to preferably eliminate the virus. Such an approach appears to have been accomplished with the world-wide elimination of the virus responsible for smallpox. This was achieved by a highly successful campaign of surveillance and containment by vaccination in order to prevent its spread, rather than by universal routine immunization.

Keywords

Respiratory Syncytial Virus Antiviral Activity Thymidine Kinase Genital Herpes Ribonucleotide Reductase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • William H. Prusoff
    • 1
  • Tai-Shun Lin
    • 1
  • William R. Mancini
    • 1
  • Michael J. Otto
    • 1
  • Scott A. Siegel
    • 1
  • J. J. Lee
    • 1
  1. 1.Department of PharmacologyYale University School of MedicineNew HavenUSA

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