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Stepwise Changes in Crossbridge State and Sarcomere Length: Do Lattice Constraints Play a Critical Role?

  • C. J. Ritz-Gold
  • C. M. Gold
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37)

Abstract

Observed abrupt and stepwise changes in crossbridge state induced by MgPPi in skeletal fibers using spin label techniques as well as stepwise changes in sarcomere length in actively contracting fibers are considered in terms of a model based on the principles of catastrophe theory and nucleation of structural transitions in mechanically constrained polymeric assemblies.

Keywords

Potential Energy Surface Catastrophe Theory Stepwise Change Cusp Catastrophe Spin Label Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Delay, M.J., Ishide, N., Jacobson, R.C., Pollack, G.H. and Tirosh, R. (1981). Stepwise sar- comere shortening: analysis by high-speed cinemicrography. Science 213: 1523–1525.PubMedCrossRefGoogle Scholar
  2. Oosawa, F. and Higashi, S. (1967). Statistical thermodynamics of polymerization and polymorphism of protein. Prog. Theor. Biol. 1: 79–165.Google Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • C. J. Ritz-Gold
    • 1
  • C. M. Gold
    • 1
  1. 1.841 HSW, Cardiovascular Research InstituteUniversity of CaliforniaSan FranciscoUSA

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