A Proposed Mechanism of Contraction in which Stepwise Shortening is a Basic Feature

  • Gerald H. Pollack
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37)


A simple model is put forth as an initial attempt to account for the observation that the contractile process is discrete and sychronized over a large region of space.


Thin Filament Thick Filament Global Synchrony Contractile Mechanism Activate Force Generator 
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  1. Flory, P.J. (1956). Role of Crystallization in Polymers and Proteins. Science 124: 53–60.PubMedCrossRefGoogle Scholar
  2. McLachlan, A.D., and Kam, J. (1982). Periodic charge distributions in the myosin rod amino acid sequence match cross-bridge spacings in muscle. Nature 299: 228–231.CrossRefGoogle Scholar
  3. Pollack, G.H. (1983) The sliding filament/cross-bridge theory: A critical review. Physiological Reviews, in press.Google Scholar
  4. Tsong, T.Y., Karr, T. and Harrington, W.F. (1979). Rapid helix-coil transitions in the S-2 region of myosin. Proc. Natl. Acad. Sci. USA 76(3): 1109–1113PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Gerald H. Pollack
    • 1
  1. 1.Division of Bioengineering and Department of Anesthesiology, WD-12University of WashingtonSeattleUSA

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