Structural Dynamics: Implications for Contractile Mechanisms
NOBLE We would now like to have a general discussion about structure and I would suggest that we should be thinking not just in anatomical terms. We should be thinking in terms of the relevance of this to the mechanisms of muscle physiology. So perhaps I could set the ball rolling by reminding you of the study that Dr. Rowe presented in which, following dissolution of the myosin and reconstitution, he could regrow, as it were, the filament lattice, and if this was done at a very long sarcomere length, he obtained a sarcomere, which if I remember correctly, had a gap between the two half sarcomeres.
KeywordsActin Filament Thin Filament Sarcomere Length Thick Filament Myosin Filament
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