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An Actomyosin Motor

  • H. Shimizu
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37)

Abstract

I would like to report some results obtained by Yano, Yamamoto and myself on a novel system (Yano et al., 1982) we have named the actomyosin motor in which a rotor with attached F-actin rotates in a specific direction, driven by the ATP-splitting interaction with active fragments of myosin, heavy meromyosin or subfragment-1, in a solution containing MgATP. The actomyosin motor is not only interesting as a new kind of motor made of biological material but also, as a stream cell (Yano, 1978; Yano et al., 1978; Yano & Shimizu, 1978; Shimizu & Yano, 1978; Shimizu, 1979), is suitable for the study of chemo-mechanical coupling by actin and active fragments of myosin. Active motion of the motor was observed in almost 100% of the experiments, when carefully performed.

Keywords

Actin Filament Thin Filament Arrow Head Cyanogen Bromide Active Fragment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • H. Shimizu
    • 1
  1. 1.Faculty of Pharmaceutical SciencesThe University of TokyoHongo, Bunkyo-ku, Tokyo 113Japan

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