Change in Fixed-Charge in the Thick Filament Lattice of Limulus Striated Muscle with Sarcomere Shortening

  • P. Brink
  • M. M. Dewey
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37)


A highly significant increase in fixed-charge occurs in the A-bands of Limulus striated muscle following activation and sarcomere shortening. This is in striking contrast to vertebrate striated muscle. Treatment with either papain or alkaline phosphatase reduces this fixed-charge. The increase in charge may serve as a motive force in thick filament shortening.


Donnan Potential Equilibrium Potential Myosin Head Thick Filament Rigor Solution 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • P. Brink
    • 1
  • M. M. Dewey
    • 1
  1. 1.Department of Anatomical SciencesState University of New York at Stony BrookStony BrookUSA

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