Change in Fixed-Charge in the Thick Filament Lattice of Limulus Striated Muscle with Sarcomere Shortening
A highly significant increase in fixed-charge occurs in the A-bands of Limulus striated muscle following activation and sarcomere shortening. This is in striking contrast to vertebrate striated muscle. Treatment with either papain or alkaline phosphatase reduces this fixed-charge. The increase in charge may serve as a motive force in thick filament shortening.
KeywordsDonnan Potential Equilibrium Potential Myosin Head Thick Filament Rigor Solution
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