Panic Disorder

Medical and Psychological Parameters
  • Rolf G. Jacob
  • Mark D. Rapport


Panic, as an individual experience, is an extreme form of anxiety or terror. Usually panic tends to occur in life-threatening situations, especially when it is unclear whether avenues of escape are available. An informative, subjective account of such intense anxiety was provided by Casey (1978), who described his experience of waking up from general anesthesia while remaining com pletely paralyzed by curare. Such experiences of panic can have profound and long-lasting effects. For example, Campbell, Sanderson, and Laverty (1964) reported a finding, later dramatized in the film Clockwork Orange, that stimuli classically conditioned to brief episodes of Scoline-induced respiratory paralysis produced conditioned anxiety responses that failed to habituate, even after 300 extinction trials extending over several months.


Generalize Anxiety Disorder Panic Disorder Panic Attack Mitral Valve Prolapse Anticipatory Anxiety 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Agras, W.S., & Jacob, R. G. Phobia: Nature and measurement. In D. H. Barlow & M. Mavissakalian (Eds.), Phobia: Psychological and pharmacological treatment. New York: Guil ford Press, 1981.Google Scholar
  2. Alarcon R., Dickinson, W., & Dohn, H. Flashback phenomena: Clinical and diagnostic dilem mas. Journal of Nervous and Mental Disease ,1982, 170 ,217–223.PubMedGoogle Scholar
  3. Allen, J. P., Imbus, C. E., Powers, D. R., & Haywood, L. J. Neurological impairment induced by hyperventilation in children with sickle cell anemia. Pediatrics ,1976, 58 ,124–126.PubMedGoogle Scholar
  4. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (3rd ed.). Washington D.C.: Author, 1980.Google Scholar
  5. Andrews, J. Psychotherapy of phobias. Psychological Bulletin ,1966, 66 ,455–480.PubMedGoogle Scholar
  6. Anthony D., Dippe, S., Hofeldt, F. D., Davis, J. W., & Forsham, P. H. Personality disorder and reactive hypoglycemia: A quantitative study. Diabetes ,1973, 22 ,664–675.PubMedGoogle Scholar
  7. Ascher, L. M. Employing paradoxical intention in the treatment of agoraphobia. Behaviour Research and Therapy ,1981, 19 ,533–542.PubMedGoogle Scholar
  8. Barlow, J. B., & Pocock, W. A. Mitral valve prolapse, the specific billowing mitral leaflet syn drome, or an insignificant nonejection systolic click. American Heart Journal ,1975, 90 ,636–655.PubMedGoogle Scholar
  9. Barnett, H. J. M., Boughner, D. R,, Taylor, D. W., Cooper, P. E., Kostuk, W. J., & Nichol, P. M. Further evidence relating mitral valve prolapse to cerebral ischemic events. New England Journal of Medicine ,1980, 302 ,139–144.PubMedGoogle Scholar
  10. Bateson, G. Steps to an ecology of mind; Collected essays in anthropology, psychiatry, evolution and epistemology. San Francisco: Chandler, 1972.Google Scholar
  11. Beard, G. Neurasthenia, or nervous exhaustion. The Boston Medical and Surgical Journal ,1869, 3 ,217–221.Google Scholar
  12. Beck, A. T., Laude, R., & Bohnert, M. Ideational components of anxiety neurosis. Archives of General Psychiatry ,1974, 31 ,319–325.PubMedGoogle Scholar
  13. Blau, J. N. Migraine: A vasomotor instability of the meningeal circulation. The Lancet ,1978, 1136–1139.Google Scholar
  14. Bowlby, J. Attachment and loss. In J. Bowlby (Ed.), Psychology of attachment and loss series: Vol. 3. Separation, anxiety and anger. London: The Hogarth Press, 1973.Google Scholar
  15. Brown, E. B. Jr. Physiological effects of hyperventilation. Psychological Reviews ,1953, 33 ,445–471.Google Scholar
  16. Brown, H. N., & Kemble, S. B. Episodic anxiety and cardiac arrhythmias. Psychosomatics ,1981, 22 ,907–915.PubMedGoogle Scholar
  17. Campbell, D., Sanderson, R. E., & Laverty, S. G. Characteristics of a conditional response in human subjects during extinction trials following a single traumatic conditioning trial. Journal of Abnormal Psychology ,1964, 68 ,627–639.Google Scholar
  18. Casey, J. F. A psychiatrist’s experience of terror. Psychiatric Annals ,1978, 8 ,250–254.Google Scholar
  19. Chambless, D., Foa, E., Groves, G., & Goldstein, A. Flooding with Brevital in the treatment of agoraphobia: Countereffective? Behaviour Research and Therapy ,1979, 17 ,243–251.PubMedGoogle Scholar
  20. Cheitlin, M. D., & Byrd, R. L. The click-murmur syndrome-a clinical problem in diagnosis and treatment. Journal of the American Medical Association ,1981, 245 ,1357–1361.PubMedGoogle Scholar
  21. Clancy, J., Noyes, R., Jr., Hoenk, P. R., & Slymen, D. J. Secondary depression in anxiety neurosis. Journal of Nervous and Mental Disease ,1978, 166 ,846–850.PubMedGoogle Scholar
  22. Compernolle, T., Hoogduin, K., & Joele, L. Diagnosis and treatment of the hyperventilation syndrome. Psychosomatics ,1979, 20 ,622–625.Google Scholar
  23. Coryell, W., Noyes, R., & Clancy, J. Excess mortality in panic disorder -A comparison with primary unipolar depression. Archives of General Psychiatry ,1982, 39 ,701–703.PubMedGoogle Scholar
  24. Curtis, G. C. Sensory experiences during treatment of phobias by in vivo exposure. American Journal of Psychiatry ,1981, 138 ,1095–1097.PubMedGoogle Scholar
  25. Darsee, J. R., Mikolich, J. R., Nicoloff, N. B., & Lesser, L. E. Prevalence of mitral valve prolapse in presumably healthy young men. Circulation ,1979, 59 ,619–622.PubMedGoogle Scholar
  26. Davison, G. C., & Valins, S. Maintenance of self-attributed and drug-attributed behavior change. Journal of Personality and Social Psychology ,1969, 11 ,25–33.PubMedGoogle Scholar
  27. Dealy, R. S., Ishiki, D. M., Avery, D. H., Wilson, L. G., & Dunner, D. C. Secondary depression in anxiety disorders. Comprehensive Psychiatry ,1981, 22 ,612–618.PubMedGoogle Scholar
  28. Devereux, R. B., Perloff, J. K., Reichek, N., & Josephson, M. E., Mitral valve prolapse. Circulation ,1976, 54 ,3–14.PubMedGoogle Scholar
  29. Drachman, D. A., & Hart, C. W. An approach to the dizzy patient. Neurology ,1972, 22 ,323–334.PubMedGoogle Scholar
  30. Dudley, D. L., Holmes, T. H., Martin, C. J., & Ripley, H. S. Changes in respiration associated with hypnotically induced emotion. Psychosomatic Medicine ,1964, 26 ,46–57.PubMedGoogle Scholar
  31. Emmelkamp, P. M. G., & Wessels, H. Flooding in imagination vs. flooding in vivo: A comparison with agoraphobics. Behaviour Research and Therapy ,1975, 13 ,7–15.PubMedGoogle Scholar
  32. Emmelkamp, P. M. G., Kuipers, C. M., & Eggeraat, J. B. Cognitive modification versus pro longed exposure in vivo. Behaviour Research and Therapy ,1978, 16 ,33–41.PubMedGoogle Scholar
  33. Engel, G. L., Ferris, E. B., & Logan, M. Hyperventilation: Analysis of clinical symptomatology. Annuals of Internal Medicine ,1947, 27 ,683–704.Google Scholar
  34. Epstein, A. W. Body image and alterations during seizures and dreams of epileptic. Archives of Neurology ,1967, 16 ,613–619.PubMedGoogle Scholar
  35. Evans, I. A conditioning model of a common neurotic pattern-fear of fear. Psychotherapy: Theory, Research and Practice ,1972, 9 ,238–241.Google Scholar
  36. Everaerd, W. T. A. M., Rijken, H. M., & Emmelkamp, P. M. G. A comparison of flooding and successive approximation in the treatment of agoraphobia. Behaviour Research and Ther apy ,1973, 11 ,105–117.Google Scholar
  37. Eysenck, H. J. A theory of the incubation of anxiety/fear responses. Behaviour Research and Therapy ,1968, 6 ,309–321.PubMedGoogle Scholar
  38. Fabry, J. B., Bulka, R. P., & Sahakian, W. S. Logotherapy in action. New York: Jason Aronson, Inc., 1979.Google Scholar
  39. Fazekas, J. F., McHenry, L. C., Alman, R. W., & Sullivan, J. F. Cerebral hemodynamics during brief hyperventilation. Archives of Neurology ,1961, 4 ,132–138.PubMedGoogle Scholar
  40. Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R., Winokur, G., & Munoz, R. Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry ,1972, 26 ,57–63.PubMedGoogle Scholar
  41. Feldman, L. Anxiety. . . Panic, Researchers are testing new treatments. The Emissary ,1980, 12.Google Scholar
  42. Folgering, H., & Colla, P. Some anomalies in the control of PaCO2 in patients with a hyperventilation syndrome. Bulletin Europeen de Physiopathologie Respiratoire ,1978, 14 ,503–512.PubMedGoogle Scholar
  43. Ford, C. V., Bray, G. A., & Swerdloff, R. S. A psychiatric study of patients referred with a diagnosis of hypoglycemia. American Journal of Psychiatry ,1976, 133 ,290–294.PubMedGoogle Scholar
  44. Forrest, R. D. Mitral valve prolapse syndrome in anxiety neurosis. American Heart Journal ,1981, 102 ,139.PubMedGoogle Scholar
  45. Frankl, V. D. Paradoxical intention and deflection. Psychotherapy: Theory, research and practice ,1975, 12 ,226–236.Google Scholar
  46. Freedman, A., Dornbush, R., & Shapiro, B. Anxiety: Here today and here tomorrow. Compre hensive Psychiatry ,1981, 22 ,44–53.Google Scholar
  47. Freud, S. On the grounds for detaching a particular syndrome from neurasthenia under the description “Anxiety neurosis.” In J. Strachey (Ed. & Transl.). The standard edition of the complete psychological works of Sigmund Freud (Vol. 3). London: The Hogarth Press, 1962 (Originally published, 1895).Google Scholar
  48. Freud, S. Inhibitions, symptoms and anxiety. In J. Strachey (Ed. & Transl.), The standard edition of the complete psychological works of Sigmund Freud (Vol. 20). London: The Hogarth Press, 1959 (Originally published, 1926).Google Scholar
  49. Freud, S. Anxiety and instinctual life; New introductory lecture #32. In J. Strachey (Ed. & Transl.), The standard edition of the complete psychological works of Sigmund Freud (Vol. 22). London: The Hogarth Press, 1964 (Originally published, 1933).Google Scholar
  50. Fry, W. The marital context of an anxiety syndrome. Family Process ,1962, 1 ,245–252.Google Scholar
  51. Garssen, B. Role of stress in the development of the hyperventilation syndrome. Psychotherapy and Psychosomatics ,1980, 33 ,214–225.PubMedGoogle Scholar
  52. Gawin, F., & Markoff, R. Panic anxiety after abrupt discontinuation of amitriptyline. American Journal of Psychiatry ,1981, 138 ,117–118.PubMedGoogle Scholar
  53. Gelder, M. Behaviour therapy for anxiety states. British Medical Journal ,1969, 691–694.Google Scholar
  54. Gelder, M. G., Bancroft, J. H. J., Gath, D. H., Johnston, D. W., Mathews, A. M., & Shaw, P. M. Specific and non-specific factors in behavior therapy. British Journal of Psychiatry ,1973, 123 ,445–462.PubMedGoogle Scholar
  55. Gerz, H. Experience with logotherapeutic technique of paradoxical intention in the treatment of phobic and obsessive-compulsive patients. American Journal of Psychiatry ,1966, 123 ,548–553.PubMedGoogle Scholar
  56. Girodo, M. Yoga meditation and flooding in the treatment of anxiety neurosis. Journal of Behavior Therapy & Experimental Psychiatry ,1974, 5 ,157–160.Google Scholar
  57. Gliebe, P., & Auerback, A. Sighing and other forms of hyperventilation simulating organic disease. Journal of Nervous and Mental Disease ,1944, 99 ,600–615.Google Scholar
  58. Glynn, C., Lloyd, J., & Folkhard, S. Ventilatory response to intractable pain. Pain ,1981, 11 ,201–211.PubMedGoogle Scholar
  59. Goldstein, A., & Chambless, D. A reanalysis of agoraphobia. Behavior Therapy ,1978, 9 ,47–59.Google Scholar
  60. Gotoh, F., Meyer, J., & Takagi, Y. Cerebral effects of hyperventilation in man. Archives of Neurology ,1965, 72, 410.Google Scholar
  61. Gray, J. A., Davis, N., Feldon, J., Nicholas, J., Rawlins, P., & Owen, S. R. Animal models of anxiety. Progress in neuro-psychopharmacology ,1981, 5 ,143–157.PubMedGoogle Scholar
  62. Guten, S., & Allen, V. L. Likelihood of escape, likelihood of danger and panic behavior. The Journal of Social Psychology ,1972, 87 ,29–36.PubMedGoogle Scholar
  63. Hadji-Georgopoulos, A., Schmidt, M., Margolis, S., & Kowarski, A. Elevated hypoglycemic index and late hyperinsulinism in symptomatic postprandial hypoglycemia. Journal of Clinical Endocrinology and Metabolism ,1980, 50 ,371–376.PubMedGoogle Scholar
  64. Hafner, R. J. The husbands of agoraphobic women and their influence on treatment outcome. British Journal of Psychiatry ,1977, 131 ,289–294.PubMedGoogle Scholar
  65. Hafner, R. J., & Marks, I. M. Exposure in vivo of agoraphobics; contributions of diazepam, group exposure and anxiety evocation. Psychological Medicine ,1976, 6 ,71–88.PubMedGoogle Scholar
  66. Hafner, J., & Milton, F. The influence of propranolol on the exposure in vivo of agoraphobics. Psychological Medicine ,1977, 7 ,419–425.PubMedGoogle Scholar
  67. Hale, F., Margen, S., & Rabak, D. Postprandial hypoglycemia and “psychological” symptoms. Biological Psychiatry ,1981, 17 ,125–130.Google Scholar
  68. Hall, R., Popkin, M., Devaul, R., Faillace, L., & Stickney, S. Physical illness presenting as psychiatric disease. Archives of General Psychiatry ,1978, 35 ,1315–1320.PubMedGoogle Scholar
  69. Hall, R. C. W. Anxiety. In R. C. W. Hall (Ed.), Psychiatric presentations of medical illness. New York: S. P. Medical and Scientific Books, 1980.Google Scholar
  70. Harper, M., & Roth, M. Temporal lobe epilepsy and the phobic anxiety depersonalization syndrome. A comparative study, Parts I and II. Comprehensive Psychiatry ,1962, 3 ,129–151 & 215-226.Google Scholar
  71. Hecker, E. Über larvirte und abortive Angstzustände bei Neurasthenie. Zentralblatt für Nervenheilkunde ,1893, 4 ,565.Google Scholar
  72. Herr, J. J., & Weakland, J. H. Counseling elders and their families: Practical techniques for applied geronotology. New York: Springer, 1979.Google Scholar
  73. Hickam, J. B., Cargill, W. H., & Golden, A. Cardiovascular reactions to emotional stimulus effect on cardiac output, A-V O2 difference, arterial pressure and peripheral resistance. Journal of Clinical Investigation ,1948, 27 ,290–298.Google Scholar
  74. Hill, O. The hyperventilation syndrome. British Journal of Psychiatry ,1979, 135 ,367–368.PubMedGoogle Scholar
  75. Hoehn-Saric, R. Neurotransmitters in anxiety. Archives of General Psychiatry ,1982, 39 ,735–742.PubMedGoogle Scholar
  76. Hoehn-Saric, R., Frank, J., Imber, S., Nash, E., Stone, A., & Battle, C. Systematic preparation of patients for psychotherapy-I. Effects on therapy behavior and outcome. Journal of Psychiatric Research ,1964, 2 ,267–281.Google Scholar
  77. Hollon, S. D., & DuRubeis, R. J. Placebo-psychotherapy combinations: Inappropriate representations of psychotherapy in drug-psychotherapy comparative trials. Psychological Bulletin ,1981, 90 ,467–477.PubMedGoogle Scholar
  78. Jacob, R. G., & Turner, S. M. Somatoform disorders. In S. M. Turner & M. Hersen (Eds.), Adult Psychopathology and Diagnosis. New York: Wiley, 1984.Google Scholar
  79. Jacob, R. G., Moller, M. B., Turner, S. M., & Wall, C., III. Otoneurological dysfunction in patients with panic disorder or agoraphobia with panic attacks. Presented at the 17th Annual Convention, The World Congress on Behavior Therapy, Washington, D. C., Dec. 8-11, 1983.Google Scholar
  80. Janis, I., Chapman, D., Gillin, J., & Speigel, J. The problem of panic. In D. P. Schultz (Ed.), Panic behavior: Discussion and readings. New York: Random House, 1964.Google Scholar
  81. Johnson, D., Dorr, K., Swenson, W., & Service, J. Reactive hypoglycemia. Journal of the Amer ican Medical Association ,1980, 243 ,1151–1155.Google Scholar
  82. Kantor, J. S., Zitrin, C. M., & Zeldis, S. M. Mitral valve prolapse syndrome in agoraphobic patients. American Journal of Psychiatry ,1980, 137 ,467–469.PubMedGoogle Scholar
  83. Kerr, W. J., Dalton, J. W., & Gliebe, P. A. Some physical phenomena associated with anxiety states and their relation to hyperventilation. Annals of Internal Medicine ,1937, 11 ,961–992.Google Scholar
  84. Kimmel, H., & Brennan, A. Conditioning models of anxiety. International Journal of Psychology ,1981, 16 ,371–387.Google Scholar
  85. King, A. Penelzine treatment of Roth’s calamity syndome. Medical Journal of Australia ,1962, 1 ,879–883.Google Scholar
  86. Klein, D. F., & Fink, M. Psychiatric reaction patterns to imipramine. American Journal of Psy chiatry ,1962, 119 ,432–438.Google Scholar
  87. Koryani, E. K. Somatic illness in psychiatric patients. Psychosomatics ,1980, 21 ,887–891.Google Scholar
  88. Lader, M., & Mathews, A. M. A physiological model of phobic anxiety and desensitization. Behaviour Research and Therapy ,1968, 6 ,411–421.PubMedGoogle Scholar
  89. Lader, M., & Mathews, A. Physiological changes during spontaneous panic attacks. Journal of Psychosomatic Research ,1970, 14 ,377–382.PubMedGoogle Scholar
  90. Lamb, L., Dermksian, G., & Sarnoff, C. Significant cardiac arrhythmias induced by common respiratory maneuvers. American Journal of Cardiology ,1958, 2 ,563–571.PubMedGoogle Scholar
  91. Lary, D., & Goldschlager, N. Electrocardiogram changes during hyperventilation resembling myocardial ischemia in patients with normal coronary arteriograms. American Heart Jour nal ,1974, 87 ,383–390.Google Scholar
  92. Latimer, P. Carbon dioxide as a reciprocal inhibitor in the treatment of neurosis. Journal of Behavior Therapy and Experimental Psychiatry ,1977, 8 ,83–85.Google Scholar
  93. Lavallee, Y., Lamontagne, Y., Pinard, G., Annable, L., & Tetreault, L. Effects on EMG feedback, diazepam and their combination on chronic anxiety. Journal of Psychomatic Research ,1977,21,65–71.Google Scholar
  94. Leboeuf, A., & Lodge, J. A comparison of frontalis EMG feedback training and progressive relaxation in the treatment of chronic anxiety. British Journal of Psychiatry ,1980, 137 ,279–284.PubMedGoogle Scholar
  95. Leitenberg, H., Agras, S., Barlow, D., & Oliveau, D. Contribution of selective positive reinforcement and therapeutic instructions to systematic desensitization therapy. Journal of Abnor mal Psychology ,1969, 74 ,114–118.Google Scholar
  96. Lewis, B. I. Chronic hyperventilation syndrome. Journal of the American Medical Association ,1954, 14 ,1204–1208.Google Scholar
  97. Lewis, B. I. Hyperventilation syndrome: A clinical and physiological evaluation. California Med icine ,1959, 91 ,121–126.Google Scholar
  98. Lewis, B. I., Seebohm, P. M., Hamilton, W. K., January, L. E., & Wheeler, P. Continuous biophysical recording techniques in the study of cardiopulmonary phenomena accompanying psychogenic hyperventilation. Psychosomatic Medicine ,1955, 17 ,479.Google Scholar
  99. Lipsedge, M., Hajioff, J., Huggins, P., Napier, L., Pearce, J., Pike, D., & Rich, M. The man agement of severe agoraphobia: A comparison of Iproniazid and systematic desensitization. Psychopharmacologia ,1973, 32 ,67–80.PubMedGoogle Scholar
  100. Lum, L. C. Hyperventilation: The tip and the iceberg. Journal of Psychosomatic Research ,1975, 19 ,375–383.PubMedGoogle Scholar
  101. Lum, L. C. The syndrome of habitual chronic hyperventilation. In P. Hill (Ed.), Modern trends in psychosomatic medicine (Vol. 3). London: Butterworths, 1976.Google Scholar
  102. Malleson, N. Panic and phobia: A possible method of treatment. The Lancet ,1959, 225–227.Google Scholar
  103. Markiewicz, W., Stoner, J., London, E., Hunt, S. A. ,& Popp, R. L. Mitral valve prolapse in 100 presumably healthy young females. Circulation ,1976, 53 ,464–473.PubMedGoogle Scholar
  104. Marks, I. M. Fears and phobias. New York: Academic, 1969.Google Scholar
  105. Marks, I. M. The classification of phobic disorders. British Journal of Psychiatry ,1970, 116 ,377–386.PubMedGoogle Scholar
  106. Marks, I. M., Gelder, M. G., & Edwards, G. Hypnosis and desensitization for phobias: A controlled prospective trial. British Journal of Psychiatry ,1968, 114 ,1263–1274.PubMedGoogle Scholar
  107. Marks, I., Boulougouris, J., & Marset, P. Flooding vs. desensitization in the treatment of phobic patients: A crossover study. British Journal of Psychiatry ,1971, 119 ,353–375.PubMedGoogle Scholar
  108. Mavissakalian, M. Personal communication, 1982.Google Scholar
  109. May, R. The meaning of anxiety. New York: Norton, 1977.Google Scholar
  110. McCaul, K., Solomon, S., & Holmes, D. Effects of paced respiration and expectations on physiological and psychological responses to threat. Journal of Personality and Social Psychology ,1979, 37 ,564–571.PubMedGoogle Scholar
  111. McCormick, W. O. Declining-dose drug desensitization for phobias. Canadian Psychiatric Association Journal ,1973, 18 ,33–40.PubMedGoogle Scholar
  112. McNair, D. M., & Fisher, S. Separating anxiety from depression. In M. A. Lipton, A. DiMascio & K. F. Killam (Eds.), Psychopharmacology: A generation of progress. New York: Raven Press, 1978.Google Scholar
  113. McNair, D. M., & Kahn, R. J. Imipramine compared with a benzodiazepine for agoraphobia. In D. F. Klein & J. G. Rabkin (Eds.), Anxiety: New research and changing concepts. New York: Raven Press, 1981.Google Scholar
  114. Meyer, J. S., & Gotoh, F. Metabolic and electroencephalographic effects of hyperventilation. Archives of Neurology ,1960, 5 ,539–552.Google Scholar
  115. Mills, J. N. Hyperapnoea induced by forced breathing. Journal of Physiology ,1946, 105 ,95–116.Google Scholar
  116. Motta, P. E., Fagiani, M. D., Dolcetti, A., Bellone, E., & Borello, G. Modificazioni del gas nel sangue nello attacco ansioso di media gravità. Archivo per le scienze Mediche ,1971, 128 ,111–119.Google Scholar
  117. Neill, W. A., & Hattenhauer, M. Impairment of myocardial O2 supply due to hyperventilation. Circulation ,1975, 52 ,854–858.PubMedGoogle Scholar
  118. Noyes, R., Clancy, J., Hoenk, P. R., & Sylmen, D. J. Anxeity neurosis and physical illness. Comprehensive Psychiatry ,1978, 19 ,407–413.PubMedGoogle Scholar
  119. Okel, B. B., & Hurst, J. W. Prolonged hyperventilation in man. Archives of Internal Medicine ,1961, 108 ,757–762.PubMedGoogle Scholar
  120. Pariser, S. F., Pinta, E. R., & Jones, B. A. Mitral valve prolapse syndrome and anxiety neurosis/ panic disorder. American Journal of Psychiatry ,1978, 135 ,246–247.PubMedGoogle Scholar
  121. Pariser, S. F., Jones, B. A., Pinta, E. R., Young, E. A., & Fontana, M. E. Panic attacks: Diagnostic evaluations of 17 patients. American Journal of Psychiatry ,1979, 136 ,105.PubMedGoogle Scholar
  122. Permutt, M. A. Postprandial hypoglycemia. Diabetes ,1976, 25 ,719–733.PubMedGoogle Scholar
  123. Permutt, M. A. Is it really hypoglycemia? If so, what should you do? Medical Times ,1980, 108 ,35–43.PubMedGoogle Scholar
  124. Pitts, F. N., & McClure, J. N. Lactate metabolism in anxiety neurosis. New England Journal of Medicine ,1967, 277 ,1328–1336.Google Scholar
  125. Protass, L. M. Possible precipitation of cerebral thrombosis in sickle cell anemia by hyperventi-lation. Annals of Internal Medicine ,1973, 79 ,451.PubMedGoogle Scholar
  126. Raichle, M., & Plum, F. Hyperventilation and cerebral blood flow. Stroke ,1972, 3 ,566–575.PubMedGoogle Scholar
  127. Ramm, E., Marks, I. M., Yuksel, S., & Stern, R. S. Anxiety management training for anxiety states: Positive compared with negative self-statements. British Journal of Psychiatry, 1982, 140 ,367–373.PubMedGoogle Scholar
  128. Raskin, M., Johnson, G., & Rodestvedt, J. Chronic anxiety treated by feedback-induced muscle relaxation. Archives of General Psychiatry ,1973, 28 ,263–267.PubMedGoogle Scholar
  129. Raskin, M., Bali, L., & Peeke, H. Muscle biofeedback and transcendental meditation in chronic anxiety. Archives of General Psychiatry ,1980, 37 ,93–97.PubMedGoogle Scholar
  130. Raskin, M., Peeke, H., Dickman, W., & Pinsker, H. Panic and generalized anxiety disorders-development antecedents and precipitants. Archives of General Psychiatry ,1982, 39 ,687– 689.PubMedGoogle Scholar
  131. Rice, R. L. Symptom patterns of the hyperventilation syndrome. Annals of Internal Medicine, 1950, 8 ,691–700.Google Scholar
  132. Riley, D. J. The “oily” paper bag and hyperventilation. Journal of the American Medical Association ,1974, 229 ,638.PubMedGoogle Scholar
  133. Roberts, W. W. Normal and abnormal depersonalization. Journal of Mental Science ,1960,106, 478–493.PubMedGoogle Scholar
  134. Sarason, I. G. Life stress, self-preoccupation and social supports. Office of Naval Research (code 452). Organizational Effectiveness Research Program, Arlington, Virginia 22217. Contract No. N00014-75-C-0905, NR-170-804, April 15, 1979.Google Scholar
  135. Sargant, W. The treatment of anxeity states and atypical depressions by the monoamine oxidase inhibitor drugs. Journal of Neuropsychiatry ,1962, 3 ,Supp. 1, 96–103.Google Scholar
  136. Selvini-Palazzoli, M., Cecchin, G., Prata, G., & Boscolo, L. Paradox and counterparadox: A new model in the therapy of the family in schizophrenic transaction. New York: Jason Aronson, 1978.Google Scholar
  137. Sheehan, D. V., Ballenger, J., & Jacobson, G. Treatment of endogenous anxiety with phobic hysterical and hypochondrical symptons. Archives of General Psychiatry ,1980, 37 ,51–59.PubMedGoogle Scholar
  138. Shraberg, D. The phobic anxiety-depersonalization syndrome. Psychiatric Opinion ,1977, Nov/ Dec., 35–40.Google Scholar
  139. Spiegel, H. X., & Spiegel, D. Trance and treatment: Clinical uses of hypnosis. New York: Basic Books, 1978.Google Scholar
  140. Spitzer, R. L., Endicott, J., & Robins, E. Research diagnostic criteria. (3rd ed.) New York: New York State Psychiatric Institute Division of Biometrics Research, 1980.Google Scholar
  141. Stern, R., & Marks, I. Brief and prolonged flooding: A comparison in agoraphobic patients. Archives of General Psychiatry ,1973, 28 ,270–276.PubMedGoogle Scholar
  142. Suess, W. M., Alexander, A. B., Smith, D. D., Sweeney, H. W. & Marion, R. J. The effects of psychological stress on respiration: A preliminary study of anxiety and hyperventilation. Psychophysiology ,1980, 17 ,535–540.PubMedGoogle Scholar
  143. Townsend, R., House, J., & Addario, D. A comparison of biofeedback-mediated relaxation and group therapy in the treatment of chronic anxiety. American Journal of Psychiatry ,1975, 132 ,6.Google Scholar
  144. Turner, S. M., Jacob, R. G., & Morrison, R. Somatoform and factitious disorders. In H. E. Adams & P. B. Sutker (Eds.), Comprehensive handbook of psychopathology. New York: Plenum Press, 1984.Google Scholar
  145. Ursin, H., Baade, E., & Levine S. (Eds.), Psychobiology of stress: A study of coping men. New York: Academic Press, 1978.Google Scholar
  146. Varela, J. A. Can social psychology be applied? In M. Deutsch and H. A. Hornstein (Eds.), Applying social psychology: Implications for research, practice and training. New York: Halsted Press, 1975.Google Scholar
  147. Venkatesh, A., Pauls, D., Crow, R., Noyes, R., Van Valkenburg, C., Martins, J. B., & Kerber, R. E. Mitral valve prolapse in anxeity neurosis. American Heart Journal ,1980, 100 ,302–305.PubMedGoogle Scholar
  148. Waites, T. Hyperventilation-chronic and acute. Archives of Internal Medicine ,1978, 38 ,1700–1701.Google Scholar
  149. Walker, L. The prognosis of affective illness with overt anxiety. Journal of Neurology, Neurosurgery and Psychiatry ,1959, 22 ,338–341.Google Scholar
  150. Watson, J. P., & Marks, I. M. Relevant and irrelevant fear in flooding-a crossover study of phobic patients. Behavior Therapy ,1971, 2 ,275–293.Google Scholar
  151. Watzlawick, P., Beavin, J., & Jackson, D. D. Pragmatics of human communication. New York: Norton, 1967.Google Scholar
  152. Watzlawick, P., Weakland, J., & Fisch, R. Change: Principles of problem formation and prob lem resolution. New York: Norton, 1974.Google Scholar
  153. Weeks, C. Simple, effective treatment of agoraphobia. New York: Hawthorn Books, 1977.Google Scholar
  154. Wheatley, C. E. Hyperventilation syndrome: A frequent cause of chest pain. Chest ,1975, 68 ,195–199.PubMedGoogle Scholar
  155. Wicklund, R. A. Freedom and reactance. Hillsdale, N. J.: Lawrence Erlbaum Associates, 1974.Google Scholar
  156. Wildenthal, K., Fuller, D., & Shapiro, W. Paroxysmal atrial arrhythmias induced by hyperventilation. The American Journal of Cardiology ,1968, 21 ,436–441.PubMedGoogle Scholar
  157. Woodruff, R. A., Guze, S. G., & Clayton, P. J. Anxiety neurosis among psychiatric outpatients. Comprehensive Psychiatry ,1972, 13 ,165–170.PubMedGoogle Scholar
  158. Wooley, C. F. Where are the diseases of yesteryear? Circulation ,1976, 53 ,749–751.PubMedGoogle Scholar
  159. Yager, J., & Young, R. J. Nonhypoglycemia is an epidemic condition. New England Journal of Medicine ,1974, 291 ,907–908.PubMedGoogle Scholar
  160. Yates, A. J. The application of learning theory to the treatment of tics. Journal of Abnormal and Social Psychology ,1958, 36 ,175–182.Google Scholar
  161. Yu, P. N., Yim, J. B., & Stanfie!d, C. A. Hyperventilation syndrome: Changes in electrocardiogram, blood gases, and electrolytes during voluntary hyperventilation: Possible mechanisms and clinical implications. Archives of Internal Medicine ,1959, 103 ,902–913.PubMedGoogle Scholar
  162. Zitrin, C. M., Klein, D. F., & Woerner, M. G. Treatment of agoraphobia with group exposure in vivo and imipramine. Archives of General Psychiatry ,1980, 37 ,63–72.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Rolf G. Jacob
    • 1
  • Mark D. Rapport
    • 2
  1. 1.Department of Psychiatry, Western Psychiatric Institute and ClinicUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Department of PsychologyUniversity of Rhode IslandKingstonUSA

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