Transplantation of the Developing Mammalian Visual System

  • Steven C. McLoon
  • Linda K. McLoon


Processing of the visual image in the brain requires an orderly relay of information between the various visual centers. This is accomplished by having these visual centers interconnect in very precise patterns. A good example of this is the projection of the retinal ganglion cells to the brain. The axons of the ganglion cells course along a well-defined tract, enter only very specific nuclei in the brain, and within these nuclei terminate in a retinotopic fashion such that neighboring retinal ganglion cells terminate in neighboring areas of the central visual nuclei. A major problem in developmental neurobiology is to determine how these patterns of connections develop. The transplantation technique affords one method by which to study this problem.


Ganglion Cell Superior Colliculus Inferior Colliculus Amacrine Cell Ganglion Cell Layer 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Steven C. McLoon
    • 1
  • Linda K. McLoon
    • 1
  1. 1.Departments of Anatomy and OphthalmologyUniversity of MinnesotaMinneapolisUSA

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