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Lymphocyte Transfer for Cancer Therapy

Prerequisites for Efficacy and the Use of Long-Term Cultured T Lymphocytes
  • Martin A. Cheever
  • Philip D. Greenberg
  • Alexander Fefer

Abstract

Tumor cells express surface antigens that can serve as targets for immunologic attack. It has long been known that T lymphocytes can respond to and specifically kill these cells in vitro. If such lymphocytes could be obtained in sufficient numbers, their adoptive transfer into a tumor-bearing host should provide berefit in tumor therapy.

Keywords

Spleen Cell Donor Cell Adoptive Immunotherapy Syngeneic Tumor Chromium Release Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Martin A. Cheever
    • 1
    • 2
  • Philip D. Greenberg
    • 1
    • 2
  • Alexander Fefer
    • 1
    • 2
  1. 1.Division of OncologyUniversity of Washington School of MedicineSeattleUSA
  2. 2.Fred Hutchinson Cancer Research CenterSeattleUSA

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