The Biochemist’s Approach to the Problem

  • Thomas J. Kindt
  • J. Donald Capra


Mixtures of antibodies were sufficient for serologic studies since extremely specific antisera could detect micrograms of an idiotype present in milligrams of an immunoglobulin mixture. The ground rules for the biochemical analysis of antibodies, however, are completely different. These studies require large amounts of antibodies that are not only directed against a single specificity, but that represent a single protein moiety.


Light Chain Heavy Chain Versus Region Hypervariable Region Complete Amino Acid Sequence 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Thomas J. Kindt
    • 1
  • J. Donald Capra
    • 2
  1. 1.National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaUSA
  2. 2.University of Texas Health Science CenterDallasUSA

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