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Monoclonal Antibodies Directed against the Nicotinic Acetylcholine Receptor

  • David P. Richman

Abstract

The nicotinic acetylcholine receptor (AChR) is a transmembrane glycoprotein located at the neuromuscular junction (NMJ). This well-characterized receptor may be considered a model for the study of other neurotransmitter receptors and other cell membrane receptors, e.g., hormone receptors or antigen receptors. Similarly, the NMJ, because of its location remote from other synapses, represents a convenient model system for the study of synaptic transmission.

Keywords

Acetylcholine Receptor Nicotinic Acetylcholine Receptor Elapid Snake Experimental Autoimmune Myasthenia Macro Phage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • David P. Richman
    • 1
    • 2
  1. 1.Department of Neurology, Division of the Biological SciencesUniversity of ChicagoChicagoUSA
  2. 2.Pritzker School of MedicineChicagoUSA

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