The Control of Membrane Fluidity in Plasmalogen-Containing Anaerobic Bacteria

  • Howard Goldfine
Part of the Biomembranes book series (B, volume 12)


Studies on the control of membrane fluidity in living organisms have largely concentrated on the participation of diacylphospholipids and their acyl chains in these processes. The effects of additions of sterols to diacylphospholipids have also been intensively investigated. In addition to the fact that diacylphosphatides are the predominant lipid class in many biological membranes, physical studies on these lipids have been facilitated by the relative ease of chemical synthesis of pure diacylphospholipids with homogeneous acyl chains. Added to this consideration, many of the now classical studies on the biological regulation of membrane fluidity were done on mycoplasmas, acholeplasmas, and Escherichia coli, all of which contain diacyl lipids with or without sterols, as their predominant lipid types. As many of the chapters in this volume will undoubtedly attest, considerable understanding of the phase behavior of these lipids and the membranes that contain them has been achieved. In addition, progress is being made on the ther-motropic phase behavior of other major lipid classes such as sphingolipids (see Ruocco et al., 1981, for references). Ether lipids in the form of plas-malogens (1-O-alk-l′-enyl-2-acyl phosphoglycerides) and 1-O-alkyl-2-acyl phosphoglycerides are other major lipid classes in biological membranes.


Membrane Fluidity Acyl Chain Ether Lipid Exogenous Fatty Acid Clostridium Butyricum 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Howard Goldfine
    • 1
  1. 1.Department of Microbiology School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA

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