The Macrophage as a Cytotoxic Effector Cell in Mice and Humans

  • M. L. Lohmann-Matthes
  • H. Lang
  • D. Krumwieh
  • D. Sun

Abstract

Activated macrophages are now generally agreed to be cytotoxic effector cells against tumor cells and intracellular microorganisms (1). The most potent activator is the lymphokine MCF (MAF) which apparently cooperates with or is enhanced by substances like LPS (2).

Keywords

Urea Glycol Rubber Thymidine Paration 

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References

  1. 1.
    Lymphokine reports No. 3. E. Pick and M. Landy ed. in: “Macrophage activation”, Academic Press (1981).Google Scholar
  2. 2.
    Hibbs, J.B., Taintor, R.R., Chapman, H.A. and Weinberg, J.B., Science 197: 279 (1977).PubMedCrossRefGoogle Scholar
  3. 3.
    Sun, D., Krumwieh, D. and Lohmann-Matthes, M.L., Immunobiology 160: 120 (1981).Google Scholar
  4. 4.
    Schreiber, R.D., Altman, A. and Katz, D.H., J. T. Med. 156: 677 (1982).Google Scholar
  5. 5.
    Ratliff, T.L., Thomasson, D.L., McCool, R.E. and Catalona, W.J., Cell. Immunol. 68: 31 (1982).CrossRefGoogle Scholar
  6. 6.
    Kniep, E.M., Domzig, W., Lohmann-Matthes, M.L. and Kickhöfen, B., J. Immunol. 127: 417 (1981).PubMedGoogle Scholar
  7. 7.
    Leonard, E.J., Ruco, L.P. and Meltzer, M.S., Cell. Immunol. 41: 341 (1978).CrossRefGoogle Scholar
  8. 8.
    Lohmann-Matthes, M.L., Lang, H., Sun, D., Kickhöfen, B., in: “Lymphokines”, E. Pick Vol. 3, p. 365, Academic Press (1981).Google Scholar
  9. 9.
    Meerpohl, H.G., Lohmann-Matthes, M.L. and Fischer, H., Eur. J. Immunol. 6: 213 (1976).PubMedCrossRefGoogle Scholar
  10. 10.
    Montovani, A., Jerrelis, T.R., Deau, J.H. and Herberman, R.B., Int. J. Cancer 23: 18 (1979).CrossRefGoogle Scholar
  11. 11.
    Lang, H. and Lohmann-Matthes, M.L., Immunobiology 157: 109 (1980).PubMedCrossRefGoogle Scholar
  12. 12.
    Fidler, J.J., Science 208: 1469 (1980).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • M. L. Lohmann-Matthes
    • 1
  • H. Lang
    • 1
  • D. Krumwieh
    • 1
  • D. Sun
    • 1
  1. 1.Max-Planck-Institut für ImmunbiologieFreiburgGermany

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