Role of Macrophages in T Cell Activation

  • P. Erb
  • G. Ramila
  • A. Stern
  • I. Sklenar


There is now general agreement that the induction of any immune response is dependent on macrophages (MØ) or MØ-like cells which act as antigen presenting cells. However, beside MØ, other cells which are not considered to belong to the MØ lineage are also involved in the induction of at least some immune processes. Thus, these ‘inducer’ cells are heterogeneous and the use of the term ‘accessory cells’ (AC) or ‘antigen presenting cells’ (APC) instead of MØ seems to be more appropriate to describe these cells. However, as a lot of the evidence for antigen presentation has been obtained by studying classical MØ, the term ‘MØ’ will be further used, keeping in mind that the functional activities described will not necessarily be restricted to this particular cell type.


Spleen Cell Tumour Line Accessory Cell Peritoneal Exudate Immune Spleen Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



accessory cells


antigen presenting cell


dentric cells


genetically related MØ factor


I region associated


Ia-associated antigen complex


major histocompatibility complex


P cells

persisting cells


perito­neal exudate cells


T helper cells


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • P. Erb
    • 1
  • G. Ramila
    • 1
  • A. Stern
    • 1
  • I. Sklenar
    • 1
  1. 1.Institute for MicrobiologyUniversity of BaselBaselSwitzerland

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