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Human IgG Short-Term Sensitizing Anaphylactic Antibody: Differences in Properties from Those of IgG4

  • W. E. Parish

Abstract

Two anaphylactic antibodies are found in human sera. IgE, the classical reaginic antibody which occurs in very small amounts, which passively sensitizes human skin in vivo for four weeks or longer, and the passive sensitizing property is susceptible to heating at 56°C or treatment with reducing chemicals. The other antibody with anaphylactic or very similar properties is part of the total IgG, and at present is known as IgG S-TS, or short-term sensitizing, because it sensitizes human or monkey skin for 2 to 4 hours only. The passive sensitizing property of IgG S-TS resists heating at 56°C and resists treatment with reducing chemicals.

Keywords

Food Allergy Histamine Release Monkey Skin Human Basophil Passive Cutaneous Anaphylaxis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • W. E. Parish
    • 1
  1. 1.Environmental Safety Laboratory Unilever ResearchSharnbrook, BedfordUK

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