Development of Sensitivity to Catecholamines in Granulosa and Luteal Cells

  • Gunnar Selstam
  • Sheela Rani
  • Knut Nordenstrom
  • Ensio Norjavaara
  • Sten Rosberg
  • Kurt Ahrén
Part of the Biochemical Endocrinology book series (BIOEND, volume 1)


Catecholamines have a wide variety of physiological effects on a number of organ systems, including the nervous system, the circulation and the metabolism. The first indications that catecholamines could influence gonadal function was probably the observation that stress can depress the androgen blood level in the male (Levin et al., 1967) and the observation that the fibromuscular layer surrounding the mature follicle can increase the intrafollicular pressure and possibly promote the ovulatory process (Walles et al., 1976). The role of these effects are, however, still under debate. Catecholamines also have effects on the blood vessels of the gonads resulting in changes in blood flow (e.g. Damber et al., 1982; Selstam, 1975). The arteries are innervated (Burder, 1978), but the role of catecholamines on gonadal blood flow also remains to be investigated.


Granulosa Cell Adenylate Cyclase Corpus Luteum Adenylate Cyclase Activity Luteal Cell 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Gunnar Selstam
    • 1
  • Sheela Rani
    • 1
  • Knut Nordenstrom
    • 1
  • Ensio Norjavaara
    • 1
  • Sten Rosberg
    • 1
  • Kurt Ahrén
    • 1
  1. 1.Departments of PhysiologyUniversities of Umeåa and GothenburgSweden

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