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Regulation of Gonadotropin Receptors and Steroidogenic Responses in Cultured Leydig Tumor Cells

  • Chapter
Regulation of Target Cell Responsiveness

Part of the book series: Biochemical Endocrinology ((BIOEND,volume 1))

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Abstract

The regulation of cell surface receptors for polypeptide hormones is now recognized as an important mechanism in the regulation of target cell responsiveness (reviewed by Hazum, 1982; King and Cuatrecasas, 1981; Kaplan, 1981; Tell et al., 1978; Catt et al., 1979). Thus, changes in target cell responsiveness associated with several physiological or pathological conditions can be explained in terms of changes in the number of surface receptors (Olefsky and Ciaraldi, 1981; Archer et al., 1975; Purvis et al., 1978; Brief el et al., 1982; Klemcke and Bartke, 1981).

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Authors and Affiliations

  1. Division of Endocrinology, Vanderbilt Medical School, Nashville, TN, 37232, USA

    Mario Ascoli & Dale A. Freeman

  2. Departments of Medicine, Vanderbilt Medical School, Nashville, TN, 37232, USA

    Mario Ascoli & Dale A. Freeman

  3. Departments of Biochemistry, Vanderbilt Medical School, Nashville, TN, 37232, USA

    Mario Ascoli

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  1. Mario Ascoli
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  2. Dale A. Freeman
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Editors and Affiliations

  1. International Foundation for Biochemical Endocrinology, Blue Hill Falls, Maine, USA

    Kenneth W. McKerns

  2. Aker Hospital, Oslo, Norway

    Asbjørn Aakvaag

  3. Institute of Pathology, Oslo, Norway

    Vidar Hansson

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© 1984 Plenum Press, New York

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Ascoli, M., Freeman, D.A. (1984). Regulation of Gonadotropin Receptors and Steroidogenic Responses in Cultured Leydig Tumor Cells. In: McKerns, K.W., Aakvaag, A., Hansson, V. (eds) Regulation of Target Cell Responsiveness. Biochemical Endocrinology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4634-0_20

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