Utilization of Lipoprotein-Carried Cholesterol for Steroidogenesis by Rat Luteal Tissue

  • Jerome F. StraussIII
  • Laurie G. Paavola
  • Mindy F. Rosenblum
  • Toshinobu Tanaka
  • John T. Gwynne
Part of the Biochemical Endocrinology book series (BIOEND, volume 1)


Steroidogenic cells have the capacity to synthesize de novo the obligate precursor of their secretory products, cholesterol. However, it has become apparent that many glands rely upon extracellular sterol as substrate (Brown et al., 1979; Gwynne and Strauss, 1982; Strauss et al., 1981). This seems to be particularly true of tissues which secrete large quantities of steroid, such as the corpus luteum.


Granulosa Cell Cholesteryl Ester Sterol Ester Luteal Cell Luteinized Granulosa Cell 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Jerome F. StraussIII
  • Laurie G. Paavola
    • 1
  • Mindy F. Rosenblum
  • Toshinobu Tanaka
  • John T. Gwynne
    • 2
  1. 1.Departments of Pathology and GynecologyUniversity of Pennsylvania, School of MedicinePhiladelphiaUSA
  2. 2.Department of MedicineUniversity of North Carolina School of MedicineChapel HillUSA

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