Abstract
The techniques of subcellular fractionation and e.m. radioautography have defined novel intracellular components which participate in receptor-mediated endocytosis [1, 2]. These components have been interpreted as vesicles accumulating within the trans* Golgi apparatus (G.a.). The vesicles are highly enriched in receptors for insulin and prolactin; during receptor-mediated insulin internalization the vesicles concentrate reasonably intact insulin prior to donation of hormone to a catabolic compartment (probably the secondary lysosome).
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References
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© 1984 Plenum Press, New York
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Bergeron, J.J.M., Khan, M.N., Posner, B.I. (1984). Insulin Internalization as Studied by Subcellular Fractionation and Electron-Microscopic Radioautography. In: Reid, E., Cook, G.M.W., Morré, D.J. (eds) Investigation of Membrane-Located Receptors. Methodological Surveys in Biochemistry and Analysis, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4631-9_23
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DOI: https://doi.org/10.1007/978-1-4684-4631-9_23
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